[PDF][PDF] Recent Developments and Biological Activities of 2-Aminothiazole Derivatives.

ME Khalifa - Acta Chimica Slovenica, 2018 - researchgate.net
Aminothiazole nuclei and their various derivatives have been long used as precursors for
the synthesis of biologically active molecules. As a typical heterocyclic amine, 2 …

Synthesis and anti-inflammatory activities of some thiazolo [3, 2-a] pyrimidine derivatives

B Tozkoparan, M Ertan, P Kelicen, R Demirdamar - Il Farmaco, 1999 - Elsevier
Sixteen new 2-benzylidene-7-methyl-3-oxo-5-(substituted phenyl)-2, 3-dihydro-5H-thiazolo
[3, 2-a] pyrimidine-6-carboxylic acid methyl esters (1a–4d) have been synthesized by …

Versatile 2-amino-4-substituted-1, 3-thiazoles: synthesis and reactions

MA Metwally, E Abdel-Latif, FA Amer… - Journal of Sulfur …, 2004 - Taylor & Francis
Syntheses and reactions of 2-amino-4-substituted-1, 3-thiazoles are reviewed in a formal
way. The title compounds are most easily accessible by various approaches, and even …

Synthesis of Some New 1,2,3,4-Tetrahydropyrimidine-2- thiones and Their Thiazolo[3,2-a]pyrimidine Derivatives as Potential Biological Agents

JD Akbari, PK Kachhadia, SD Tala… - … , Sulfur, and Silicon …, 2008 - Taylor & Francis
Some new N-(4-chlorophenyl)-6-methyl-4-aryl-2-thioxo-1, 2, 3, 4-tetrahydro pyrimidine-5-
carboxamide 4 (a–h) were synthesized by the reaction of N-(4-chlorophenyl)-3 …

Dipyrimido [4, 5-b: 5, 4-e][1, 4] thiazine: synthesis and their enzyme inhibitory activity assessment on soybean 15-lipoxygenase

A Karimian, H Eshghi, M Bakavoli, A Shiri… - Journal of the Iranian …, 2015 - Springer
A series of new derivatives of dipyrimido [4, 5-b: 5, 4-e][1, 4] thiazine were synthesized by
treatment of 5-amino-6-methyl-2-morpholino-4-pyrimidinethiol (1) with 5-bromo-2, 4-dichloro …

Novel synthesis and biological activity of 2‐substituted derivatives of 3‐cyano‐4‐imino‐2‐methylthio‐8‐methoxy‐4H‐pyrimido[2,1‐b][1,3]benzothiazole and 3‐amino‐4‐imino‐8‐methoxy …

SG Badne, DK Swamy, VN Bhosale… - Journal of …, 2011 - Wiley Online Library
Amino‐6‐methoxybenzothiazole 1 on reaction with bis (methylthio) methylene malononitrile
2 in the presence of dimethyl formamide and catalytic amount of anhydrous potassium …

Simple and efficient synthesis of substituted pyrimido[2,1-b][1,3]thiazines

SP Vartale, SB Sirsat, NK Halikar - Heterocyclic Communications, 2013 - degruyter.com
Simple and efficient synthesis of a novel fused bicyclic heterocyclic compound 3 by the
reaction of ethyl 2-cyano-3, 3-bis (methylthio) acrylate and thiourea in the presence of …

Synthesis of New Derivatives of 4‐(4,7,7‐Trimethyl‐7,8‐dihydro‐6H‐benzo[b]pyrimido[5,4‐e][1,4]thiazin‐2‐yl)morpholine

A Karimian, H Eshghi, M Bakavoli… - Journal of Heterocyclic …, 2017 - Wiley Online Library
Cyclocondensation of 5‐amino‐6‐methyl‐2‐morpholinopyrimidine‐4‐thiol (1) and 2‐bromo‐
5, 5‐dimethylcyclohexane‐1, 3‐dione (2) under mild reaction condition afforded 4, 7, 7 …

[PDF][PDF] Simple and efficient synthesis of novel fused bicyclic heterocycles pyrimido-thiazine and their derivatives

B Sirsat Shivraj, P Vartale Sambhaji - Organic Chem Curr Res, 2012 - academia.edu
We report simple and efficient synthesis of novel fused bicyclic heterocyclic compounds 3
using bis (methylthio) methylene malononitrile 1 and thiourea 2 with potassium carbonate in …

Synthesis of new derivatives of 4-(4-methyl-5H-pyrimido[4,5-b][1,4]thiazin-2-yl)morpholine and 4-methyl-2-(piperidin-1-yl)-5H-pyrimido[4,5-b][1,4]thiazine

A Karimian, H Karimian - Journal of Chemical Research, 2017 - journals.sagepub.com
Several derivatives of the novel 4-(4-methyl-5 H-pyrimido [4, 5-b][1, 4] thiazin-2-yl)
morpholine and 4-methyl-2-(piperidin-1-yl)-5 H-pyrimido [4, 5-b][1, 4] thiazine ring systems …