Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …

Positive strand RNA viruses replicate in the cytoplasm of infected cells and induce
intracellular membranous compartments harboring the sites of viral RNA synthesis. These …

Hepatitis C Virus (HCV) infects over 150 million people worldwide. In most cases HCV
infection becomes chronic, causing liver disease ranging from fibrosis to cirrhosis and …

Acyl-CoA: glycerol-3-phosphate acyltransferase (GPAT) and acyl-CoA: 1-acyl-glycerol-3-
phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol …

Viruses are obligate intracellular pathogens that are dependent on cellular machineries for
their replication. Recent technological breakthroughs have facilitated reliable identification …

The lipid phosphatase Sac1 dephosphorylates phosphatidylinositol 4‐phosphate (PI4P),
thereby holding levels of this crucial membrane signaling molecule in check. Sac1 regulates …

HCV (hepatitis C virus) is a member of the Flaviviridae family that contains a single‐stranded
positive‐sense RNA genome of approximately 9600 bases. HCV is a major causative agent …

Retromer and sorting nexins (SNXs) transport cargoes from endosomes to the trans-Golgi
network or plasma membrane. Recent studies have unveiled the emerging roles for retromer …

Phosphatidylinositol lipids play vital roles in lipid signal transduction, membrane recognition,
vesicle transport, and viral replication. Previous studies have revealed that SAC1-like …

The spike (S) glycoprotein of SARS-CoV-2 mediates viral entry through associating with
ACE2 on host cells. Intracellular trafficking and palmitoylation of S protein are required for its …