Kidney damage varies according to the primary insult. Different aetiologies of acute kidney
injury (AKI), including kidney ischaemia, exposure to nephrotoxins, dehydration or sepsis …

Computational models have made a major contribution to the field of physiology. As the
complexity of our understanding of biological systems expands, the need for computational …

Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of
acute kidney injury of various origins, and may also promote progression from acute injury to …

Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of
acute kidney injury of various origins, and may also promote progression from acute injury to …

The renal cortex drives renal function. Hypoxia/reoxygenation are primary factors in
ischemia-reperfusion (IR) injuries, but renal oxygenation per se is complex and awaits full …

Cisplatin is highly effective and one of the most commonly used chemotherapeutic agents in
the treatment of a number of different solid organ tumors. Unfortunately, the dose-limiting …

2 composed of three major sections with distinct roles;(1) the glomerulus that filters the
blood,(2) the tubule that primarily reabsorbs vital nutrients and secretes solutes, and (3) the …