Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are significant public
health concerns around the world. Despite decreasing incidence, there is still a significant …

Acute rheumatic fever is a major cause of heart disease in large parts of the world, but it
remains unknown why only a small fraction of those who are infected with rheumatogenic …

There is a pressing need to reduce the high global disease burden of rheumatic heart
disease (RHD) and its harbinger, acute rheumatic fever (ARF). ARF is a classical example of …

Background Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare form of uveitis.
Previously, the authors had demonstrated a strong association of human leukocyte antigen …

Rheumatic heart disease (RHD) is a heritable inflammatory condition characterized by
carditis, arthritis, and systemic disease. Although remaining neglected, the last 3 years has …

Background Rheumatic heart disease (RHD), the only long term consequence of acute
rheumatic fever, remains a leading cause of morbidity and mortality among young adults in …

Angiotensin converting enzyme (ACE) gene polymorphism was previously studied in some
cardiovascular diseases. There are only few studies which investigated this polymorphism in …

Poststreptococcal sequelae, especially acute rheumatic fever/rheumatic heart disease
continues to occur in significant proportions in many parts of the world, especially in less …

In underdeveloped nations like India, rheumatic heart disease (RHD) is a serious public
health concern that significantly increases cardiac morbidity and mortality. It is a progressive …

Among the various candidate genes predisposing for cardiovascular diseases, HLA-DRB1*
and IL-1β+ 3953C/T alleles have been implicated repeatedly. To test these in South India …