Tumors resurrect an embryonic vascular program to escape immunity

EJM Huijbers, KA Khan, RS Kerbel, AW Griffioen - Science immunology, 2022 - science.org
Tumors can escape immunity through multiple mechanisms, one of which is by enforcing a
state of unresponsiveness of the tumor vasculature to inflammatory cytokines. This results in …

Comparative matrix metalloproteinase-2 and-9 expression and activity during endotheliochorial and hemochorial trophoblastic invasiveness

G Gualdoni, GG Castro, R Hernández, C Barbeito… - Tissue and Cell, 2022 - Elsevier
To establish a functional placenta, its development needs adequate trophoblastic
invasiveness. The intricate and complex morphological and molecular aspects regulating …

Galectin-9 alleviates LPS-induced preeclampsia-like impairment in rats via switching decidual macrophage polarization to M2 subtype

ZH Li, LL Wang, H Liu, KP Muyayalo… - Frontiers in …, 2019 - frontiersin.org
Dysfunction of decidual macrophages (DMs) is considered a critical event in the
pathogenesis of pre-eclampsia (PE). T cell immunoglobulin mucin 3 (Tim-3) is an important …

Extracellular vesicles generated by placental tissues ex vivo: A transport system for immune mediators and growth factors

W Fitzgerald, N Gomez‐Lopez, O Erez… - American Journal of …, 2018 - Wiley Online Library
Problem To study the mechanisms of placenta function and the role of extracellular vesicles
(EV s) in pregnancy, it is necessary to develop an ex vivo system that retains placental …

A pattern recognition receptor C‐type lectin TcCTL14 contributes to immune response and development in the red flour beetle, Tribolium castaneum

Y Zhang, H Ai, Y Wang, P Zhang, L Du, J Wang… - Insect …, 2023 - Wiley Online Library
Evidence is accumulating that pattern recognition receptor (PRR) C‐type lectins (CTL) play
essential roles in recognition of pathogens. TcCTL14 (accession no. TC00871) contains the …

Overexpression of galectin-4 in placentas of women with gestational diabetes

S Schrader, L Unverdorben, S Hutter, J Knabl… - Journal of Reproductive …, 2022 - Elsevier
Objective Galectins are known for their immunomodulatory functions in placentas. They are
associated with pregnancy disorders such as preeclampsia, HELLP-Syndrome and …

Placental glycoredox dysregulation associated with disease progression in an animal model of superimposed preeclampsia

SM Blois, PD Prince, S Borowski, M Galleano… - Cells, 2021 - mdpi.com
Pregnancies carried by women with chronic hypertension are at increased risk of
superimposed preeclampsia, but the placental pathways involved in disease progression …

Decidual cells and decidualization in the carnivoran endotheliochorial placenta

ME Diessler, R Hernández, G Gomez Castro… - Frontiers in Cell and …, 2023 - frontiersin.org
Decidualization is considered a distinctive feature of eutherian pregnancy, and has
appeared during evolution along with the development of invasive forms of placentation, as …

A C-type lectin TcCTL1 is required for embryogenesis in Tribolium castaneum

Y Zhang, P Zhang, R Yu, B Li - Developmental & Comparative Immunology, 2023 - Elsevier
C-type lectin S group (CTL-S) plays a variety of roles in invertebrate including pathogen
recognition and activation of immune responses. Previous studies have shown that CTL-S …

Extracellular matrix in epitheliochorial, endotheliochorial and haemochorial placentation and its potential application for regenerative medicine

ARA da Anunciação, AM Mess… - … in Domestic Animals, 2017 - Wiley Online Library
Contents A placenta is defined as structural approximation of maternal and foetal tissues to
perform physiological exchange. Associated processes of differentiation and the …