Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders

A Bhat, B Ray, AM Mahalakshmi, S Tuladhar… - Pharmacological …, 2020 - Elsevier
Phosphodiesterases (PDE) are a diverse family of enzymes (11 isoforms so far identified)
responsible for the degradation of cyclic adenosine monophosphate (cAMP) and cyclic …

Protective effect of natural products against Huntington's disease: an overview of scientific evidence and understanding their mechanism of action

PT Lum, M Sekar, SH Gan, SR Bonam… - ACS chemical …, 2021 - ACS Publications
Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of characteristic psychiatric disturbances and …

Phytotherapeutic alternatives for neurodegenerative dementias: Scientific review, discussion and therapeutic proposal

N Acero, T Ortega, V Villagrasa, G Leon… - Phytotherapy …, 2023 - Wiley Online Library
The incidence and prevalence of age‐related neurodegenerative dementias have been
increasing. There is no curative therapy and conventional drug treatment can cause …

A clinical study and future prospects for bioactive compounds and semi-synthetic molecules in the therapies for Huntington's disease

MR Islam, MH Jony, GK Thufa, S Akash, PS Dhar… - Molecular …, 2024 - Springer
A neurodegenerative disorder (ND) refers to Huntington's disease (HD) which affects
memory loss, weight loss, and movement dysfunctions such as chorea and dystonia. In the …

[HTML][HTML] Cordia sebestena leaf extract mediated biosynthesis of silver nanoparticles, characterization, and screening of its antimicrobial activities

RS Sancheti, S Samreen, AB Gite, PN Patil… - Green Analytical …, 2023 - Elsevier
Abstract Biosynthesized Silver nanoparticles (AgNPs) are attracting interest due to their
special biological applications as well as biologically active secondary metabolites from …

Role of natural products in alleviation of Huntington's disease: An overview

M Gupta, N Singh, B Singh, P Alam - South African Journal of Botany, 2022 - Elsevier
Huntington's disease (HD) is an autosomal cognitive impairment neurodegenerative
disorder that is characterized by behavioral and psychiatric disorders followed by dementia …

Potential Anti-Toxoplasmosis Efficiency of Phoenix dactylifera Extracts Loaded on Selenium Nanoparticles

MH Wakid, MN Alsulami, M Farid… - Infection and Drug …, 2023 - Taylor & Francis
Background Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii that infects
humans and many types of mammals and birds. Objective To investigate the effect of …

Comparative microscopic assessments of the effect of aqueous and ethanol extracts of Phoenix dactylifera L. in a rat model of mercury-triggered hippocampal …

AN Agbon, HO Kwanashie, WO Hamman… - Nigerian Journal of …, 2021 - ojshostng.com
Mercury is an environmental neurotoxicant that triggers structural and physiological
alterations in different brain parts. The hippocampus is associated with learning and …

[HTML][HTML] Fractionation and determination of chemical and physical properties of Dates' fibers

SNK Al-Shaaibi, A Al-Alawi, I Al-Marhobi… - Journal of the Saudi …, 2022 - Elsevier
Dates are considered as highly nutritious and healthy food. It is a rich source of DF including
pectin, cellulose, hemicellulose, and lignin. The present study aims to fraction and …

[HTML][HTML] A comparative study on the hepatoprotective effect of selenium-nanoparticles and dates flesh extract on carbon tetrachloride induced liver damage in albino …

GN Ouais, DM Hassan - Anatomy & Cell Biology, 2023 - ncbi.nlm.nih.gov
Exposure to environmental pollutants such as carbon tetrachloride (CCL 4) causes liver
damage. This study aimed to compare the ameliorative activity of the dates flesh extract …