Protein–protein interactions regulating α-synuclein pathology

J Wang, L Dai, S Chen, Z Zhang, X Fang… - Trends in …, 2024 - cell.com
Parkinson's disease (PD) is a neurodegenerative disease characterized by the
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and …

The impact of hUC MSC–derived exosome-nanoliposome hybrids on α-synuclein fibrillation and neurotoxicity

F Aliakbari, K Marzookian, S Parsafar, H Hourfar… - Science …, 2024 - science.org
Amyloid aggregation of α-synuclein (αSN) protein amplifies the pathogenesis of
neurodegenerative diseases (NDs) such as Parkinson's disease (PD). Consequently …

[HTML][HTML] AIMP2 restricts EV71 replication by recruiting SMURF2 to promote the degradation of 3D polymerase

J Ren, L Yu, Q Zhang, P Ren, Y Cai, X Wang, K Lan… - Virologica Sinica, 2024 - Elsevier
Hand, foot and mouth disease (HFMD), mainly caused by enterovirus 71 (EV71), has
frequently occurred in the Asia-Pacific region, posing a significant threat to the health of …

Dual inhibition of aminoacyl-tRNA synthetase interacting multifunctional protein-2 and α-synuclein by steroid derivative is neuroprotective in Parkinson's model

JY Shin, MW Ha, JH Kim, J Cheon, GH Lee, SM Paek… - iScience, 2024 - cell.com
Aminoacyl-tRNA synthetase interacting multifunctional protein-2 (AIMP2), a parkin substrate,
possesses self-aggregating properties, potentiating α-synuclein aggregation and …

[PDF][PDF] A2-astrocyte activation by short term hypoxia rescue α-synuclein preformed fibril induced neuronal cell death

HN Choi, SH Kim, B Lee, HS Yoo, JH Lee, MG Jo… - 2024 - scholar.archive.org
Parkinson's disease (PD) is a neuro-degenerative disease for which a radical cure is not
available, only symptomatic control. Studies have shown that hypoxia may have disease …

[引用][C] Dual inhibition of aminoacyl-tRNA synthetase interacting multifunctional protein-2 and a-synuclein by steroid derivative is neuroprotective in Parkinson's model

T Thioflavin