Genetic insights into the neurodevelopmental origins of schizophrenia

R Birnbaum, DR Weinberger - Nature Reviews Neuroscience, 2017 - nature.com
Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of
neurobiological investigation. Although the underlying causal mechanisms remain …

Oxidative stress‐related mechanisms in schizophrenia pathogenesis and new treatment perspectives

EA Ermakov, EM Dmitrieva… - Oxidative Medicine …, 2021 - Wiley Online Library
Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …

Sex differences in the developing brain: insights from multimodal neuroimaging

AN Kaczkurkin, A Raznahan… - …, 2019 - nature.com
Youth (including both childhood and adolescence) is a period when the brain undergoes
dramatic remodeling and is also a time when neuropsychiatric conditions often emerge …

The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological …

M Pruessner, AE Cullen, M Aas, EF Walker - … & Biobehavioral Reviews, 2017 - Elsevier
Over the past decade, our understanding of the role of stress in serious mental illness has
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …

Childhood trauma in schizophrenia: current findings and research perspectives

D Popovic, A Schmitt, L Kaurani, F Senner… - Frontiers in …, 2019 - frontiersin.org
Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms
throughout adult life in most of the affected patients. This unfavorable course is associated …

Childhood adversities and psychosis: evidence, challenges, implications

C Morgan, C Gayer‐Anderson - World psychiatry, 2016 - Wiley Online Library
There is a substantial body of research reporting evidence of associations between various
forms of childhood adversity and psychosis, across the spectrum from experiences to …

The impact of environmental factors in severe psychiatric disorders

A Schmitt, B Malchow, A Hasan, P Falkai - Frontiers in neuroscience, 2014 - frontiersin.org
During the last decades, schizophrenia has been regarded as a developmental disorder.
The neurodevelopmental hypothesis proposes schizophrenia to be related to genetic and …

[HTML][HTML] Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank

L Nobis, SG Manohar, SM Smith, F Alfaro-Almagro… - NeuroImage: Clinical, 2019 - Elsevier
Measurement of hippocampal volume has proven useful to diagnose and track progression
in several brain disorders, most notably in Alzheimer's disease (AD). For example, an …

Developmental trajectories of amygdala and hippocampus from infancy to early adulthood in healthy individuals

A Uematsu, M Matsui, C Tanaka, T Takahashi… - 2012 - journals.plos.org
Knowledge of amygdalar and hippocampal development as they pertain to sex differences
and laterality would help to understand not only brain development but also the relationship …

The social hippocampus

A Montagrin, C Saiote, D Schiller - Hippocampus, 2018 - Wiley Online Library
The concept of cognitive map has been proposed as a way to organize our experiences and
guide behavior across all domains of cognition. The hippocampus has been identified as the …