Extracellular vesicles (EV), which include exosomes and microvesicles, are secreted from
virtually every cell. EV contain mRNA, miRNA, lipids and proteins and can deliver this …

The most common cause of untreatable vision loss is dysfunction of the retina. Conditions,
such as age-related macular degeneration, diabetic retinopathy and glaucoma remain …

Retinal ischemia is a major cause of vision loss and impairment and a common underlying
mechanism associated with diseases such as glaucoma, diabetic retinopathy, and central …

The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects
underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) …

Retinal ischemia–reperfusion (RIR) injury is involved in the pathogenesis of various vision‐
threatening diseases. The overproduction of reactive oxygen species (ROS) is thought to be …

Mesenchymal stem cell (MSCs)-derived extracellular vesicles (EVs) are emerging
therapeutic tools. Hypoxic pre-conditioning (HPC) of MSCs altered the production of …

The human mesenchymal stem cell (hMSC) secretome has pleiotropic effects which
underpin their therapeutic potential. hMSC serum-free conditioned media (SFCM) has been …

Purpose: Exosomes derived from human mesenchymal stem cells (hMSCs) cultured under
hypoxic conditions contain proteins and growth factors that promote angiogenesis. This …

Purpose: To determine whether priming of bone marrow mesenchymal stem cells (MSCs) by
signals from injured retina, particularly tumor necrosis factor α (TNFα), increase their …

Transplantation of bone marrow mesenchymal stem cells (BM-MSCs) can protect
cardiomyocytes against anthracycline-induced cardiomyopathy (AIC) through paracrine …