Pulmonary hypertension in preterm infants with bronchopulmonary dysplasia

CD Baker, SH Abman, PM Mourani - Pediatric allergy, immunology …, 2014 - liebertpub.com
Bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity, is a significant
contributor to perinatal morbidity and mortality. Premature birth disrupts pulmonary vascular …

Fetal immune response to chorioamnionitis

SG Kallapur, P Presicce, CM Rueda… - Seminars in …, 2014 - thieme-connect.com
Chorioamnionitis is a frequent cause of preterm birth and is associated with an increased
risk for injury responses in the lung, gastrointestinal tract, brain, and other fetal organs …

Interdisciplinary care of children with severe bronchopulmonary dysplasia

SH Abman, JM Collaco, EG Shepherd… - The Journal of …, 2017 - jpeds.com
Advances in perinatal care have dramatically im-proved survival of extremely preterm infants
and the incidence of bronchopulmonary dysplasia (BPD) has not changed over the past few …

Antenatal determinants of bronchopulmonary dysplasia and late respiratory disease in preterm infants

LA Morrow, BD Wagner, DA Ingram… - American journal of …, 2017 - atsjournals.org
Rationale: Mechanisms contributing to chronic lung disease after preterm birth are
incompletely understood. Objectives: To identify antenatal risk factors associated with …

Intrauterine growth restriction decreases pulmonary alveolar and vessel growth and causes pulmonary artery endothelial cell dysfunction in vitro in fetal sheep

PJ Rozance, GJ Seedorf, A Brown… - … of Physiology-Lung …, 2011 - journals.physiology.org
Intrauterine growth restriction (IUGR) increases the risk for bronchopulmonary dysplasia
(BPD). Abnormal lung structure has been noted in animal models of IUGR, but whether …

Intratracheal administration of clinical-grade mesenchymal stem cell-derived extracellular vesicles reduces lung injury in a rat model of bronchopulmonary dysplasia

A Porzionato, P Zaramella, A Dedja… - … of Physiology-Lung …, 2019 - journals.physiology.org
Mesenchymal stem cells (MSCs) prevent the onset of bronchopulmonary dysplasia (BPD) in
animal models, an effect that seems to be mediated by their secreted extracellular vesicles …

Excess soluble vascular endothelial growth factor receptor-1 in amniotic fluid impairs lung growth in rats: linking preeclampsia with bronchopulmonary dysplasia

JR Tang, SA Karumanchi, G Seedorf… - … of Physiology-Lung …, 2012 - journals.physiology.org
Epidemiological studies have shown that maternal preeclampsia (PE) increases the risk of
bronchopulmonary dysplasia (BPD), but the underlying mechanism is unknown. Soluble …

Animal models, learning lessons to prevent and treat neonatal chronic lung disease

AH Jobe - Frontiers in medicine, 2015 - frontiersin.org
Bronchopulmonary dysplasia (BPD) is a unique injury syndrome caused by prolonged injury
and repair imposed on an immature and developing lung. The decreased septation and …

Recent advances in antenatal factors predisposing to bronchopulmonary dysplasia

E Taglauer, SH Abman, RL Keller - Seminars in perinatology, 2018 - Elsevier
Bronchopulmonary dysplasia (BPD) remains a major cause of late morbidities and death
after preterm birth. BPD is characterized by an arrest of vascular and alveolar growth and …

[PDF][PDF] Pulmonary vascular phenotypes of prematurity: the path to precision medicine

H Mirza, EW Mandell, JP Kinsella, PJ McNamara… - The Journal of …, 2023 - Elsevier
Pulmonary hypertension (PH) is associated with significant morbidities and high mortality in
preterm infants, yet mechanisms contributing to the pathogenesis of PH, the impact of early …