Gut microbiota controlling radiation-induced enteritis and intestinal regeneration

I Moraitis, J Guiu, J Rubert - Trends in Endocrinology & Metabolism, 2023 - cell.com
Cancer remains the second leading cause of mortality, with nearly 10 million deaths
worldwide in 2020. In many cases, radiotherapy is used for its anticancer effects. However …

Enteroendocrine cell regulation of the gut-brain axis

JR Barton, AK Londregan, TD Alexander… - Frontiers in …, 2023 - frontiersin.org
Enteroendocrine cells (EECs) are an essential interface between the gut and brain that
communicate signals about nutrients, pain, and even information from our microbiome …

IL-22 resolves MASLD via enterocyte STAT3 restoration of diet-perturbed intestinal homeostasis

P Zhang, J Liu, A Lee, I Tsaur, M Ohira, V Duong, N Vo… - Cell Metabolism, 2024 - cell.com
The exponential rise in metabolic dysfunction-associated steatotic liver disease (MASLD)
parallels the ever-increasing consumption of energy-dense diets, underscoring the need for …

Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains

RK Zwick, P Kasparek, B Palikuqi, S Viragova… - Nature Cell …, 2024 - nature.com
A key aspect of nutrient absorption is the exquisite division of labour across the length of the
small intestine, with individual nutrients taken up at different proximal: distal positions. For …

Obesity and diet independently affect maternal immunity, maternal gut microbiota and pregnancy outcome in mice

L Wekema, S Schoenmakers, N Schenkelaars… - Frontiers in …, 2024 - frontiersin.org
Introduction Maternal obesity poses risks for both mother and offspring during pregnancy,
with underlying mechanisms remaining largely unexplored. Obesity is associated with …

Impact of various high fat diets on gene expression and the microbiome across the mouse intestines

J Martinez-Lomeli, P Deol, JR Deans, T Jiang… - Scientific Reports, 2023 - nature.com
High fat diets (HFDs) have been linked to several diseases including obesity, diabetes, fatty
liver, inflammatory bowel disease (IBD) and colon cancer. In this study, we examined the …

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development

DH Kulkarni, B Rusconi, AN Floyd, EL Joyce… - Gut …, 2023 - Taylor & Francis
Obesity and the metabolic syndrome are complex disorders resulting from multiple factors
including genetics, diet, activity, inflammation, and gut microbes. Animal studies have …

Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population

X Li, JD Morel, G Benegiamo, J Poisson, A Bachmann… - Elife, 2023 - elifesciences.org
Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by
dietary, environmental, and genetic factors. While the incidence of IBD is increasing …

[HTML][HTML] Sugary and salty former food products in pig diets affect energy and nutrient digestibility, feeding behaviour but not the growth performance and carcass …

S Mazzoleni, M Tretola, A Luciano, P Lin, L Pinotti… - animal, 2023 - Elsevier
Former foodstuff products (FFPs) are promising alternative ingredients for reducing the
waste of natural resources and the environmental impact of food production. This study …

[HTML][HTML] Enteroendocrine cells regulate intestinal homeostasis and epithelial function

JG Nwako, HA McCauley - Molecular and Cellular Endocrinology, 2024 - Elsevier
Enteroendocrine cells (EECs) are well-known for their systemic hormonal effects, especially
in the regulation of appetite and glycemia. Much less is known about how the products made …