The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

abstract Bronchial asthma is characterized by persistent cough, increased sputum, and
repeated wheezing. The pathophysiology underlying these symptoms is the hyper …

Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …

Asthma is a T lymphocyte–controlled disease of the airway wall caused by inflammation,
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …

Electronic (e)-cigarettes theoretically may be safer than conventional tobacco. However, our
prior studies demonstrated direct adverse effects of e-cigarette vapor (EV) on airway cells …

Rationale: Rhinovirus infection is followed by significantly increased frequencies of positive,
potentially pathogenic sputum cultures in chronic obstructive pulmonary disease (COPD) …

Despite current regulations, which limit the levels of certain air pollutants, there are still a
number of adverse health effects that result from exposure to these agents. Numerous …

Dendritic cells (DCs) are generally held responsible for initiating and maintaining allergic T
helper 2 (TH2)-cell responses to inhaled allergens in asthma. Although the epithelium was …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

Cigarette smoking is a worldwide epidemic and the most prevalent cause of many diseases
leading to increased morbidity and mortality globally. The impact of smoking on …