Aging-related diseases (ARDs) are a major global health concern, and the development of
effective therapies is urgently needed. Kaempferol, a flavonoid found in several plants, has …

The amyloid cascade is the most frequently accepted hypothesis of Alzheimer's Disease
(AD). According to this hypothesis, the formation of plaques precedes the appearance of …

Background Alzheimer's disease (AD) is the most common neurodegenerative disease and
its pathogenesis is still unclear. There is dysbiosis of gut microbiota in AD patients. More …

Alzheimer's disease (AD) is a slowly progressive neurodegenerative disease
conceptualized as a continuous process, ranging from mild cognitive impairment (MCI), to …

Aim Periodontitis is caused by dysbiosis of oral microbes and is associated with increased
cognitive decline in Alzheimer's disease (AD), and recently, a potential functional link was …

Alzheimer's disease (AD) remains the most prevalent neurodegenerative disease, and no
effective treatment is available yet. Metal‐ion‐triggered aggregates of amyloid‐beta (Aβ) …

Oxidative stress due to Cu2+-triggered aggregation of β-amyloid protein (Aβ) and reactive
oxygen species (ROS) overexpression in the brain is an important hallmark of early stages …

CHRFAM7A is a relatively recent and exclusively human gene arising from the partial
duplication of exons 5 to 10 of the α7 neuronal nicotinic acetylcholine receptor subunit (α7 …

Alzheimer's disease (AD) leads to progressive declines in memory and learning. This
disease may arise from endoplasmic reticulum stress due to protein misfolding, which …

Aging is a major risk factor for many human diseases, including cognitive impairment, which
affects a large population of the elderly. In the past few decades, our understanding of the …