Photobiomodulation—underlying mechanism and clinical applications

C Dompe, L Moncrieff, J Matys… - Journal of clinical …, 2020 - mdpi.com
The purpose of this study is to explore the possibilities for the application of laser therapy in
medicine and dentistry by analyzing lasers' underlying mechanism of action on different …

Brain photobiomodulation therapy: a narrative review

F Salehpour, J Mahmoudi, F Kamari… - Molecular …, 2018 - Springer
Brain photobiomodulation (PBM) therapy using red to near-infrared (NIR) light is an
innovative treatment for a wide range of neurological and psychological conditions. Red/NIR …

Up-regulation of cerebral cytochrome-c-oxidase and hemodynamics by transcranial infrared laser stimulation: a broadband near-infrared spectroscopy study

X Wang, F Tian, DD Reddy… - Journal of Cerebral …, 2017 - journals.sagepub.com
Transcranial infrared laser stimulation (TILS) is a noninvasive form of brain
photobiomulation. Cytochrome-c-oxidase (CCO), the terminal enzyme in the mitochondrial …

Photobiomodulation for Alzheimer's disease: has the light dawned?

MR Hamblin - Photonics, 2019 - mdpi.com
Next to cancer, Alzheimer's disease (AD) and dementia is probably the most worrying health
problem facing the Western world today. A large number of clinical trials have failed to show …

Transcranial photobiomodulation and thermal stimulation induce distinct topographies of EEG alpha and beta power changes in healthy humans

X Wang, H Wanniarachchi, A Wu, F Gonzalez-Lima… - Scientific reports, 2021 - nature.com
Our recent study demonstrated that prefrontal transcranial photobiomodulation (tPBM) with
1064-nm laser enables significant changes in EEG rhythms, but these changes might result …

Photobiomodulation of cytochrome c oxidase by chronic transcranial laser in young and aged brains

FS Cardoso, DW Barrett, Z Wade… - Frontiers in …, 2022 - frontiersin.org
In cellular bioenergetics, cytochrome c oxidase (CCO) is the enzyme responsible for oxygen
consumption in the mitochondrial electron transport chain, which drives oxidative …

[HTML][HTML] Transcranial laser stimulation: mitochondrial and cerebrovascular effects in younger and older healthy adults

CL Saucedo, EC Courtois, ZS Wade, MN Kelley… - Brain stimulation, 2021 - Elsevier
Background Transcranial laser stimulation is a novel method of noninvasive brain
stimulation found safe and effective for improving prefrontal cortex neurocognitive functions …

Mechanistic aspects of photobiomodulation therapy in the nervous system

F Ramezani, A Neshasteh-Riz, A Ghadaksaz… - Lasers in Medical …, 2021 - Springer
Photobiomodulation therapy (PBMT) previously known as low-level laser therapy (LLLT) has
been used for over 30 years, to treat neurological diseases. Low-powered lasers are …

Transcranial and systemic photobiomodulation for major depressive disorder: A systematic review of efficacy, tolerability and biological mechanisms

MA Caldieraro, P Cassano - Journal of affective disorders, 2019 - Elsevier
Background Photobiomodulation (PBM) with red and near-infrared light (NIR)–also known
as Low-Level Light Therapy–is a low risk, inexpensive treatment–based on non-retinal …

Beneficial neurocognitive effects of transcranial laser in older adults

E Vargas, DW Barrett, CL Saucedo, LD Huang… - Lasers in medical …, 2017 - Springer
Transcranial infrared laser stimulation (TILS) at 1064 nm, 250 mW/cm 2 has been proven
safe and effective for increasing neurocognitive functions in young adults in controlled …