Beyond casual resemblance: rigorous frameworks for comparing regeneration across species

M Srivastava - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
The majority of animal phyla have species that can regenerate. Comparing regeneration
across animals can reconstruct the molecular and cellular evolutionary history of this …

Evolution via somatic genetic variation in modular species

TBH Reusch, IB Baums, B Werner - Trends in Ecology & Evolution, 2021 - cell.com
Somatic genetic variation (SoGV) may play a consequential yet underappreciated role in
long-lived, modular species among plants, animals, and fungi. Recent genomic data …

A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state

JF Cazet, S Siebert, HM Little, P Bertemes… - Genome …, 2023 - genome.cshlp.org
The epithelial and interstitial stem cells of the freshwater polyp Hydra are the best-
characterized stem cell systems in any cnidarian, providing valuable insight into cell type …

Pluripotent, germ cell competent adult stem cells underlie cnidarian regenerative ability and clonal growth

Á Varley, HR Horkan, ET McMahon, G Krasovec… - Current Biology, 2023 - cell.com
In most animals, pluripotency is irreversibly lost post gastrulation. By this stage, all
embryonic cells have already committed either to one of the somatic lineages (ectoderm …

The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals

CE Schnitzler, ES Chang, J Waletich… - Genome …, 2024 - genome.cshlp.org
Hydractinia is a colonial marine hydroid that shows remarkable biological properties,
including the capacity to regenerate its entire body throughout its lifetime, a process made …

A cellular and molecular analysis of SoxB-driven neurogenesis in a cnidarian

E Chrysostomou, H Flici, SG Gornik… - Elife, 2022 - elifesciences.org
Neurogenesis is the generation of neurons from stem cells, a process that is regulated by
SoxB transcription factors (TFs) in many animals. Although the roles of these TFs are well …

[HTML][HTML] The Hydra stem cell system–Revisited

TW Holstein - Cells & Development, 2023 - Elsevier
Cnidarians are> 600 million years old and are considered the sister group of Bilateria based
on numerous molecular phylogenetic studies. Apart from Hydra, the genomes of all major …

[HTML][HTML] Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration

M Salinas-Saavedra, G Krasovec, HR Horkan… - Cell reports, 2023 - cell.com
Cell fate stability is essential to maintaining" law and order" in complex animals. However,
high stability comes at the cost of reduced plasticity and, by extension, poor regenerative …

[HTML][HTML] Stem cells of aquatic invertebrates as an advanced tool for assessing ecotoxicological impacts

A Rosner, J Armengaud, L Ballarin… - Science of the Total …, 2021 - Elsevier
Environmental stressors are assessed through methods that quantify their impacts on a wide
range of metrics including species density, growth rates, reproduction, behaviour and …

The colonial cnidarian Hydractinia

U Frank, ML Nicotra, CE Schnitzler - Evodevo, 2020 - Springer
Hydractinia, a genus of colonial marine cnidarians, has been used as a model organism for
developmental biology and comparative immunology for over a century. It was this animal …