Practical recommendations for using ctDNA in clinical decision making

SA Cohen, MC Liu, A Aleshin - Nature, 2023 - nature.com
The continuous improvement in cancer care over the past decade has led to a gradual
decrease in cancer-related deaths. This is largely attributed to improved treatment and …

Evaluation of the efficacy of neoadjuvant chemotherapy for breast cancer

H Wang, X Mao - Drug design, development and therapy, 2020 - Taylor & Francis
Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for
downstaging the primary tumor in the breast and the metastatic axillary lymph node …

MRI-based quantification of intratumoral heterogeneity for predicting treatment response to neoadjuvant chemotherapy in breast cancer

Z Shi, X Huang, Z Cheng, Z Xu, H Lin, C Liu, X Chen… - Radiology, 2023 - pubs.rsna.org
Background Breast cancer is highly heterogeneous, resulting in different treatment
responses to neoadjuvant chemotherapy (NAC) among patients. A noninvasive quantitative …

Axillary pathologic complete response after neoadjuvant systemic therapy by breast cancer subtype in patients with initially clinically node-positive disease: a …

S Samiei, JM Simons, SME Engelen… - JAMA …, 2021 - jamanetwork.com
Importance An overview of rates of axillary pathologic complete response (pCR) for all
breast cancer subtypes, both for patients with and without pathologically proven clinically …

Longitudinal MRI-based fusion novel model predicts pathological complete response in breast cancer treated with neoadjuvant chemotherapy: a multicenter …

YH Huang, T Zhu, XL Zhang, W Li, XX Zheng… - …, 2023 - thelancet.com
Background Accurate identification of pCR to neoadjuvant chemotherapy (NAC) is essential
for determining appropriate surgery strategy and guiding resection extent in breast cancer …

[HTML][HTML] Complement signals determine opposite effects of B cells in chemotherapy-induced immunity

Y Lu, Q Zhao, JY Liao, E Song, Q Xia, J Pan, Y Li, J Li… - Cell, 2020 - cell.com
Understanding molecular mechanisms that dictate B cell diversity is important for targeting B
cells as anti-cancer treatment. Through the single-cell dissection of B cell heterogeneity in …

[HTML][HTML] Modern surgical treatment of breast cancer

M Riis - Annals of medicine and surgery, 2020 - Elsevier
Breast cancer is the most frequent cancer in women all over the world. The prognosis is
generally good, with a five-year overall survival rate above 90% for all stages. It is still the …

Three-year follow-up of de-escalated axillary treatment after neoadjuvant systemic therapy in clinically node-positive breast cancer: the MARI-protocol

AA van Loevezijn, MEM van der Noordaa… - Breast cancer research …, 2022 - Springer
Purpose In clinically node-positive (cN+) breast cancer patients, evidence supporting
response-guided treatment after neoadjuvant systemic therapy (NST) instead of axillary …

Current and future cancer staging after neoadjuvant treatment for solid tumors

DR Byrd, JD Brierley, TP Baker… - CA: a cancer journal …, 2021 - Wiley Online Library
Until recently, cancer registries have only collected cancer clinical stage at diagnosis, before
any therapy, and pathological stage after surgical resection, provided no treatment has been …

Prognostic significance of residual axillary nodal micrometastases and isolated tumor cells after neoadjuvant chemotherapy for breast cancer

SM Wong, N Almana, J Choi, J Hu, H Gagnon… - Annals of surgical …, 2019 - Springer
Background The prognostic significance of low-volume residual nodal disease following
neoadjuvant chemotherapy (NAC) is unknown. Methods Women with cT1–4N0–1 breast …