Synthesis, characterization, antimicrobial, density functional theory, and molecular docking studies of novel Mn (II), Fe (III), and Cr (III) complexes incorporating 4-(2 …
This work synthesized three new CrAz2, MnAz2, and FeAz2 complexes and investigated
them using IR, mass, UV spectroscopy, elemental analysis, conductivity and magnetic tests …
them using IR, mass, UV spectroscopy, elemental analysis, conductivity and magnetic tests …
Drug re‐engineering and repurposing: A significant and rapid approach to tuberculosis drug discovery
The prevalence of tuberculosis (TB) remains the leading cause of death from a single
infectious agent, ranking it above all other contagious diseases. The problem to tackle this …
infectious agent, ranking it above all other contagious diseases. The problem to tackle this …
In silico drug design strategies for discovering novel tuberculosis therapeutics
Introduction Tuberculosis remains a significant concern in global public health due to its
intricate biology and propensity for developing antibiotic resistance. Discovering new drugs …
intricate biology and propensity for developing antibiotic resistance. Discovering new drugs …
Antibacterial, antifungal, anti‐inflammatory evaluation, molecular docking, and density functional theory exploration of 2‐(1H‐benzimidazol‐2‐yl)guanidine mixed …
The aim of the present framework is to synthesize and characterize new cobalt (II)(C1),
nickel (II)(C2), and copper (II)(C3) mixed‐ligand complexes incorporating bioactive 8 …
nickel (II)(C2), and copper (II)(C3) mixed‐ligand complexes incorporating bioactive 8 …
Coumarin Hydrazone Oxime Scaffolds as Potent Anti‐tubercular Agents: Synthesis, X‐ray crystal and Molecular Docking Studies
A series of new Coumarin hydrazone oxime scaffolds were synthesised as potential anti‐TB
agents. The structures of the scaffolds were confirmed by spectroscopic and analytical …
agents. The structures of the scaffolds were confirmed by spectroscopic and analytical …
ON donor tethered copper (II) and vanadium (V) complexes as efficacious anti-TB and anti-fungal agents with spectroscopic approached HSA interactions
Antimicrobial drug resistance poses a significant threat worldwide, hence triggering an
urgent situation for developing feasible drugs. 3D-transition metal coordination complexes …
urgent situation for developing feasible drugs. 3D-transition metal coordination complexes …
Design, synthesis, molecular docking, and biological evaluation of coumarin‐thymidine analogs as potent anti‐TB agents
DS Reddy, A Sinha, MM Kurjogi… - Archiv der …, 2023 - Wiley Online Library
With the intent to discover new antituberculosis (TB) compounds, coumarin‐thymidine
analogs were synthesized using second‐order nucleophilic substitution reactions of …
analogs were synthesized using second‐order nucleophilic substitution reactions of …
[PDF][PDF] A comprehensive analysis of the role of molecular docking in the development of anticancer agents against the cell cycle CDK enzyme.
Cancer is considered one of the most lethal diseases responsible for causing deaths
worldwide. Although there have been many breakthroughs in anticancer development …
worldwide. Although there have been many breakthroughs in anticancer development …
Catalytic role in Biginelli reaction: Synthesis and biological property studies of 2‐oxo/thioxo‐1, 2, 3, 4‐tetrahydropyrimidines
The Biginelli reaction has received significant consideration in recent years due to its easily
accessible aldehyde, urea/thiourea, and active methylene compounds. When it comes to …
accessible aldehyde, urea/thiourea, and active methylene compounds. When it comes to …
Coumarin-Pyrazole Linked Carbodithioates as Potential Anti-Сancer Agents: Design, Synthesis, Biological, and Molecular Docking Investigation
A series of novel benzyl 5-(substitutedphenyl)-3-(2-oxo-2 H-chromen-3-yl)-4, 5-dihydro-1 H-
pyrazole-1-carbodithioate were obtained. The anti-cancer activity of synthesised compounds …
pyrazole-1-carbodithioate were obtained. The anti-cancer activity of synthesised compounds …