[HTML][HTML] The multirole of liposomes in therapy and prevention of infectious diseases

R Nisini, N Poerio, S Mariotti, F De Santis… - Frontiers in …, 2018 - frontiersin.org
Liposomes are closed bilayer structures spontaneously formed by hydrated phospholipids
that are widely used as efficient delivery systems for drugs or antigens, due to their capability …

[HTML][HTML] Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

X Niu, J Chen, J Gao - Asian journal of pharmaceutical sciences, 2019 - Elsevier
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,
Huntington disease and amyotrophic lateral sclerosis throw a heavy burden on families and …

[HTML][HTML] Nanoparticles as adjuvants and nanodelivery systems for mRNA-based vaccines

IM Alfagih, B Aldosari, B AlQuadeib, A Almurshedi… - Pharmaceutics, 2020 - mdpi.com
Messenger RNA (mRNA)-based vaccines have shown promise against infectious diseases
and several types of cancer in the last two decades. Their promise can be attributed to their …

[HTML][HTML] Polymer-and lipid-based gene delivery technology for CAR T cell therapy

IS Pinto, RA Cordeiro, H Faneca - Journal of Controlled Release, 2023 - Elsevier
Chimeric antigen receptor T cell (CAR T cell) therapy is a revolutionary approach approved
by the FDA and EMA to treat B cell malignancies and multiple myeloma. The production of …

The role of PTPN22 in the pathogenesis of autoimmune diseases: A comprehensive review

K Tizaoui, S Terrazzino, S Cargnin, KH Lee… - Seminars in arthritis and …, 2021 - Elsevier
The incidence of autoimmune diseases is increasing worldwide, thus stimulating studies on
their etiopathogenesis, derived from a complex interaction between genetic and …

[HTML][HTML] Genetic Polymorphism of PTPN22 in Autoimmune Diseases: A Comprehensive Review

K Tizaoui, JI Shin, GH Jeong, JW Yang, S Park, JH Kim… - Medicina, 2022 - mdpi.com
It is known that the etiology and clinical outcomes of autoimmune diseases are associated
with a combination of genetic and environmental factors. In the case of the genetic factor, the …

[HTML][HTML] Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features

B Simonis, D Vignone, OG Paz, E Donati… - Journal of Colloid and …, 2022 - Elsevier
Hypothesis The positive charge on liposome surface is known to promote the crossing of the
Blood brain barrier (BBB). However, when diastereomeric cationic gemini amphiphiles are …

Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes

N Veiga, Y Diesendruck, D Peer - Advanced Drug Delivery Reviews, 2020 - Elsevier
Abnormalities in leukocytes' function are associated with many immune related disorders,
such as cancer, autoimmunity and susceptibility to infectious diseases. Recent …

[HTML][HTML] Recent advances in mRNA vaccine delivery

L Tan, X Sun - Nano Research, 2018 - Springer
In recent years, messenger RNA (mRNA) vaccines have been intensively studied in the
fields of cancer immunotherapy and infectious diseases because of their excellent efficacy …

Candidate Genetic and Molecular Drivers of Dysregulated Adaptive Immune Responses After Traumatic Brain Injury

M Duchniewicz, JYW Lee, DK Menon… - Journal of …, 2024 - liebertpub.com
Neuroinflammation is a significant and modifiable cause of secondary injury after traumatic
brain injury (TBI), driven by both central and peripheral immune responses. A substantial …