Exacerbation of thromboinflammation by JAK2V617F mutation worsens the prognosis of cerebral venous sinus thrombosis
MC Bourrienne, V Le Cam Duchez, D Faille… - Blood …, 2024 - ashpublications.org
Cerebral venous sinus thrombosis (CVST) is an uncommon venous thromboembolic event
accounting for< 1% of strokes resulting in brain parenchymal injuries. JAK2 V617F mutation …
accounting for< 1% of strokes resulting in brain parenchymal injuries. JAK2 V617F mutation …
[HTML][HTML] Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in JAK2V617F myeloproliferative neoplasms
A Guy, G Garcia, V Gourdou-Latyszenok… - Journal of Thrombosis …, 2024 - Elsevier
Background Neutrophils participate in the pathogenesis of thrombosis through the formation
of neutrophil extracellular traps (NETs). Thrombosis is the main cause of morbidity and …
of neutrophil extracellular traps (NETs). Thrombosis is the main cause of morbidity and …
Blood cell JAKtivation aggravates cerebral venous thrombosis
B Reeves - Blood Advances, 2024 - ashpublications.org
In this issue of Blood Advances, Bourrienne et al present the first preclinical data on how the
gain-offunction JAK2 V617F mutation that underlies most myeloproliferative neoplasms …
gain-offunction JAK2 V617F mutation that underlies most myeloproliferative neoplasms …
[HTML][HTML] Thromboinflammation in ischemic cerebrovascular patients with the JAK2V617F mutation
MH Kristiansen, MK Larsen, L Massarenti, V Skov… - Thrombosis …, 2025 - Elsevier
Abstract Background The JAK2V617F mutation is a driver of Philadelphia chromosome-
negative myeloproliferative neoplasms (MPN) and is also implicated in cardiovascular …
negative myeloproliferative neoplasms (MPN) and is also implicated in cardiovascular …
Real-world data on direct oral anticoagulants in BCR::ABL1-negative myeloproliferative neoplasms (MPNs): a multicenter retrospective study on behalf of scientific …
Abstract BCR:: ABL1-negative myeloproliferative neoplasms (MPNs) pose a substantial risk
of thrombosis, leading to significant morbidity and mortality. Anticoagulant therapy …
of thrombosis, leading to significant morbidity and mortality. Anticoagulant therapy …
[HTML][HTML] Risk factors analysis and the establishment of nomogram prediction model for PICC-related venous thrombosis in patients with lymphoma: a double-center …
X Wang, JS Xu - Frontiers in Oncology, 2024 - frontiersin.org
Objective The objective of this study is to examine the risk factors associated with the
occurrence of PICC-Related Venous Thrombosis (PICC-RVTE) in individuals diagnosed …
occurrence of PICC-Related Venous Thrombosis (PICC-RVTE) in individuals diagnosed …
Molecular and Clinical Risk Factors Associated with Thrombosis and Bleeding in Myelofibrosis Patients
O Morath, C Crodel, J Rinke, I Sander… - …, 2024 - thieme-connect.com
Background The risk of thrombosis and bleeding in myelofibrosis (MF) has been historically
underappreciated. We sought to investigate potential molecular and clinical risk factors for …
underappreciated. We sought to investigate potential molecular and clinical risk factors for …
[HTML][HTML] Thrombo-Hemorrhagic Complications in Myeloproliferative Neoplasms: Etiology, Pathobiology, and Therapeutic Considerations
AG Bharadwaj, GC Okura, DM Waisman - 2024 - intechopen.com
Myeloproliferative neoplasms (MPN) are characterized by the abnormal clonal proliferation
of hematopoietic progenitor cells in the bone marrow. The three major types of MPNs are …
of hematopoietic progenitor cells in the bone marrow. The three major types of MPNs are …
Molecular, Cytogenetic, and Hematological Monitoring and Response to Treatment for Chronic Myeloid Leukemia Patients.
NAHA Bahar, MTS Al-Ouqaili… - Al-Anbar Medical …, 2024 - search.ebscohost.com
Background: A genetic abnormality in chronic myeloid leukemia (CML) involves a
translocation between the long arms of chromosomes 9 and 22, known as t (9; 22)(q34; q11 …
translocation between the long arms of chromosomes 9 and 22, known as t (9; 22)(q34; q11 …