Lung cancer is the world's leading cause of cancer death and shows strong ancestry
disparities. By sequencing and assembling a large genomic and transcriptomic dataset of …

Background: Heart failure (HF) survival has improved, and nowadays, many patients with HF
die of noncardiac causes, including cancer. Our aim was to investigate whether a causal …

ABSTRACT RNA polymerase II (Pol II) is composed of 12 subunits that collaborate to
synthesize mRNA within the nucleus. Pol II is widely recognized as a passive holoenzyme …

Deregulated transcription is a well-known characteristic of cancer cells, with differentially
expressed genes being a common feature of several cancers. Often, deregulated …

Objective To investigate the impact of SERPINA3 on the migration, invasion, and liver
metastasis of colon cancer cells. Methods Immunohistochemical staining was conducted to …

The gut microbiota Parvimonas micra has been found to be enriched in gut mucosal tissues
and fecal samples of colorectal cancer (CRC) patients compared with non-CRC controls. In …

Background Chronic non-atrophic gastritis (CNG) is the most common type of chronic
gastritis. If not actively treated, it may induce gastric cancer (GC). Western medicine is …

Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high
sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in …

Genetic modifications during development of paediatric groups 3 and 4 medulloblastoma
are responsible for their highly metastatic properties and poor patient survival rates …

Cancer stem cells (CSCs) alone can initiate and maintain tumors, but the function of non-
cancer stem cells (non-CSCs) that form the tumor bulk remains poorly understood …