Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease

F Crispi, J Miranda, E Gratacós - American journal of obstetrics and …, 2018 - Elsevier
In the modern world, cardiovascular disease is a leading cause of death for both men and
women. Epidemiologic studies consistently have suggested an association between low …

Brain-sparing in intrauterine growth restriction: considerations for the neonatologist

E Cohen, W Baerts, F van Bel - Neonatology, 2015 - karger.com
Intrauterine growth restriction (IUGR) is most commonly caused by placental insufficiency, in
response to which the fetus adapts its circulation to preserve oxygen and nutrient supply to …

Intrauterine growth restriction: impact on cardiovascular development and function throughout infancy

E Cohen, FY Wong, RSC Horne, SR Yiallourou - Pediatric research, 2016 - nature.com
Intrauterine growth restriction (IUGR) refers to the situation where a fetus does not grow
according to its genetic growth potential. One of the main causes of IUGR is uteroplacental …

Long-term follow-up of intrauterine growth restriction: cardiovascular disorders

E Demicheva, F Crispi - Fetal diagnosis and therapy, 2014 - karger.com
In the modern world, cardiovascular disorders are the leading cause of mortality in
developed countries, which in most cases undergo a long subclinical phase that can last …

Fetal cardiovascular remodeling persists at 6 months in infants with intrauterine growth restriction

M Cruz‐Lemini, F Crispi… - … in Obstetrics & …, 2016 - Wiley Online Library
Objectives Intrauterine growth restriction is associated with increased cardiovascular risk
later in life but the link between fetal disease and postnatal risk is not well‐documented. We …

Persistence of cardiac remodeling in preadolescents with fetal growth restriction

SI Sarvari, M Rodriguez-Lopez… - Circulation …, 2017 - Am Heart Assoc
Background—Fetal growth restriction (FGR) affects 5% to 10% of newborns and is
associated with increased cardiovascular mortality in adulthood. We evaluated whether …

Fetal cardiac function in late‐onset intrauterine growth restriction vs small‐for‐gestational age, as defined by estimated fetal weight, cerebroplacental ratio and uterine …

M Pérez‐Cruz, M Cruz‐Lemini… - … in Obstetrics & …, 2015 - Wiley Online Library
Objective Among late‐onset small fetuses, a combination of estimated fetal weight (EFW),
cerebroplacental ratio (CPR) and mean uterine artery (UtA) pulsatility index (PI) can predict …

Mechanisms of fetal adaptation to chronic hypoxia following placental insufficiency: a review

R Ramirez Zegarra, A Dall'Asta, T Ghi - Fetal Diagnosis and Therapy, 2022 - karger.com
Placental insufficiency is associated with reduced oxygen and nutrient supply to the fetus,
which may result in fetal growth restriction (FGR). In an attempt to cope with the hostile …

Descriptive analysis of different phenotypes of cardiac remodeling in fetal growth restriction

M Rodríguez‐López, M Cruz‐Lemini… - … in Obstetrics & …, 2017 - Wiley Online Library
Objective To identify different cardiac phenotypes among cases of fetal growth restriction
(FGR). Methods Echocardiography was performed in 126 cases with FGR (birth weight< …

Perinatal changes in cardiac geometry and function in growth‐restricted fetuses at term

O Patey, JS Carvalho… - Ultrasound in Obstetrics …, 2019 - Wiley Online Library
Objective To evaluate the effect of fetal growth restriction (FGR) at term on fetal and neonatal
cardiac geometry and function. Methods This was a prospective study of 87 pregnant …