The number of patients suffering from cancer is constantly increasing and, consequently, the
number of different chemotherapy treatments administered is increasing. Given the high …

Drug impurity profiling, ie identification, structure elucidation and quantitative determination
of impurities and degradation products in bulk drug materials and pharmaceutical …

Modified resolution and overall separation factors used to quantify the separation of complex
chromatography systems are described. These factors were proven to be applicable to the …

An HPLC method for the separation of seven cephalosporins [Cefepime (CEP), ceftazidime
(CTA), ceftizaxime (CTI), ceftriaxone (CTR), cefotaxime (COT), cefixime (CIX) and …

Box‐Behnken design was applied to optimize high performance liquid chromatography
(HPLC) conditions for the simultaneous determination of potassium sorbate, sodium …

Imatinib (INN), marketed by Novartis as Gleevec (United States) or Glivec (Europe/Australia/
Latin America), received Food & Drug Administration (FDA) approval in May 2001 and is a …

The focus of this study is development of a new, convenient, rapid and sensitive
electromembrane extraction approach (based on an ionic liquid-supported MWCNTs/ZnO …

A reversed-phase high-performance liquid chromatographic method is described for the
determination of seven quinolones in plasma and amniotic fluid. Experimental designs have …

A simple, precise, accurate stability-indicating gradient reverse phase ultra-performance
liquid chromatographic (RP-UPLC) method was developed for quantitative determination of …

ABSTRACT Imatinib inhibits Bcr-Abl, c-KIT and PDGFR kinases. It is approved for the
treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GIST) and has …