Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies
With progress in genome-wide association studies of depression, from identifying zero hits
in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …
in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …
[HTML][HTML] The miRNome of depression
Depression is an effect of complex interactions between genetic, epigenetic and
environmental factors. It is well established that stress responses are associated with …
environmental factors. It is well established that stress responses are associated with …
Decision support system for major depression detection using spectrogram and convolution neural network with EEG signals
Abstract The number of Major Depressive Disorder (MDD) patients is rising rapidly these
days following the incidence of COVID‐19 pandemic. It is challenging to detect MDD …
days following the incidence of COVID‐19 pandemic. It is challenging to detect MDD …
Polygenic risk for depression, anxiety and neuroticism are associated with the severity and rate of change in depressive symptoms across adolescence
Background Adolescence marks a period where depression will commonly onset. Twin
studies show that genetic influences play a role in how depression develops and changes …
studies show that genetic influences play a role in how depression develops and changes …
The antecedents and outcomes of persistent and remitting adolescent depressive symptom trajectories: a longitudinal, population-based English study
B Weavers, J Heron, AK Thapar, A Stephens… - The Lancet …, 2021 - thelancet.com
Background Depression often first emerges in adolescence and, for many, is a lifelong
disorder. The long-term clinical course of depression is highly variable. We aimed to …
disorder. The long-term clinical course of depression is highly variable. We aimed to …
Interpretation of Mendelian randomization using a single measure of an exposure that varies over time
TT Morris, J Heron, ECM Sanderson… - International Journal …, 2022 - academic.oup.com
Background Mendelian randomization (MR) is a powerful tool through which the causal
effects of modifiable exposures on outcomes can be estimated from observational data. Most …
effects of modifiable exposures on outcomes can be estimated from observational data. Most …
Associations of maternal diabetes during pregnancy with psychiatric disorders in offspring during the first 4 decades of life in a population-based Danish birth cohort
Importance Maternal diabetes has been suggested as a risk factor for attention-
deficit/hyperactivity disorder and autism in offspring, but evidence on its association with the …
deficit/hyperactivity disorder and autism in offspring, but evidence on its association with the …
A cross‐lagged twin study of emotional symptoms, social isolation and peer victimisation from early adolescence to emerging adulthood
G Morneau‐Vaillancourt, O Oginni… - Journal of Child …, 2023 - Wiley Online Library
Background Emotional symptoms, such as anxiety and depressive symptoms, are common
during adolescence, often persist over time, and can precede the emergence of severe …
during adolescence, often persist over time, and can precede the emergence of severe …
Super-resolution fluorescence microscopic imaging in pathogenesis and drug treatment of neurological disease
J Gong, Z Jin, H Chen, J He, Y Zhang… - Advanced Drug Delivery …, 2023 - Elsevier
Since super-resolution fluorescence microscopic technology breaks the diffraction limit that
has existed for a long time in optical imaging, it can observe the process of synapses formed …
has existed for a long time in optical imaging, it can observe the process of synapses formed …
[HTML][HTML] Polygenic risk scores for schizophrenia and major depression are associated with socio-economic indicators of adversity in two British community samples
Schizophrenia (SCZ) and major depressive disorder (MDD) are complex psychiatric
disorders which contribute substantially to the global burden of disease. Both …
disorders which contribute substantially to the global burden of disease. Both …