The rapid progress in medicine, agriculture, and allied sciences has enabled the
development of a large amount of potentially useful bioactive compounds, such as drugs …

Microplastics (MPs) are a ubiquitous pollutant detected not only in marine and freshwater
bodies, but also in tap and bottled water worldwide. While MPs have been extensively …

Deciphering the genetic code that determines how the vertebrate nervous system
assembles into neural circuits that ultimately control behavior is a fascinating and …

Early during neuromuscular development, acetylcholine receptors (AChRs) accumulate at
the center of muscle fibers, precisely where motor growth cones navigate and synapses …

The developmental neurotoxic potential of the majority of environmental chemicals and
drugs is currently undetermined. Specific in vivo studies provide useful data for hazard …

The present study examined combined effects of the insecticides thiacloprid and diazinon
and a physical stressor, elevated temperature (28, 30 and 33.5° C, control at 26° C), on …

Owing to the importance of acetylcholine as a neurotransmitter, many insecticides target the
cholinergic system. Across phyla, cholinergic signaling is essential for many neuro …

Bilateral alternation of muscle contractions requires reciprocal inhibition between the two
sides of the hindbrain and spinal cord, and disruption of this inhibition should lead to …

Genetic screens for synaptogenesis mutants have been performed in many organisms, but
few if any have simultaneously screened for defects in pre-and postsynaptic specializations …

Signaling in the nervous system requires matching of neurotransmitter receptors with
cognate neurotransmitters at synapses. The vertebrate neuromuscular junction is the best …