During the last decade, organs-on-chips or organoids microphysiological analysis platforms
(MAP) have garnered attention in the practical applications of disease models, drug …

The female reproductive system comprises the internal and external genitalia, which
communicate through intricate endocrine pathways. Besides secreting hormones that …

Quantification of fetal drug exposure remains challenging since sampling from the placenta
or fetus during pregnancy is too invasive. Currently existing in vivo (eg, cord blood sampling) …

Comprehensively understanding the female reproductive system is crucial for safeguarding
fertility and preventing diseases concerning women's health. With the capacity to simulate …

Fetal membrane (amniochorion), the innermost lining of the intrauterine cavity, surround the
fetus and enclose amniotic fluid. Unlike unidirectional blood flow, amniotic fluid subtly rocks …

Developmental toxicity testing urgently requires the implementation of human-relevant new
approach methodologies (NAMs) that better recapitulate the peculiar nature of human …

Oxidative stress (OS) and inflammation arising from cellular derangements at the fetal
membrane‐decidual interface (feto‐maternal interface [FMi]) is a major antecedent to …

Non-human animals represent a large and important feature in the history of biomedical
research. The validity of their use, in terms of reproducible outcomes and translational …

Bacterial infections with Group B Streptococcus (GBS) are an important cause of adverse
outcomes in pregnant individuals, neonates, and infants. GBS is a common commensal in …

Spontaneous preterm birth (PTB) affects around 11% of births, posing significant risks to
neonatal health due to the inflammation at the fetal–maternal interface (FMi). This …