The advent of whole-slide imaging in digital pathology has brought about the advancement
of computer-aided examination of tissue via digital image analysis. Digitized slides can now …

Context.—Novel therapeutics often target complex cellular mechanisms. Increasingly,
quantitative methods like digital tissue image analysis (tIA) are required to evaluate …

Since whole-slide imaging has been commercially available for over 2 decades, digital
pathology has become a constantly expanding aspect of the pathology profession that will …

Objectives: This study assessed diffuse myocardial fibrosis (MF) by cardiac magnetic
resonance (CMR) imaging and speckle-tracking echocardiography (STE) in patients with …

Advancements in technology and digitization have ushered in novel ways of enhancing
tissue-based research via digital microscopy and image analysis. Whole slide imaging …

Results Main pathologic findings in this single-center cohort were representative of common
diagnostic entities in the kidney allografts, with rejection (32%) and glomerulonephritides …

Historically, pathologists perform manual evaluation of H&E-or immunohistochemically-
stained slides, which can be subjective, inconsistent, and, at best, semiquantitative. As the …

Background: QuPath is an open-source digital image analyzer notable for its user-friendly
design, cross-platform compatibility, and customizable functionality. Since it was first …

Background: The histologic difference between alcoholic cardiomyopathy (ACM) and
idiopathic dilated cardiomyopathy (IDCM) is unclear. The present study aimed to identify the …

Synthetic macroporous biomaterials are widely used in the field of skin tissue engineering to
mimic membrane functions of the native dermis. Biomaterial designs can be subclassified …