Probiotics for periodontal health—Current molecular findings

T Nguyen, H Brody, A Radaic, Y Kapila - Periodontology 2000, 2021 - Wiley Online Library
Dysbiosis of the oral microbiome is associated with a variety of oral and systemic diseases,
including periodontal disease. Oral dysbiosis in periodontal disease leads to an …

Metformin for cardiovascular protection, inflammatory bowel disease, osteoporosis, periodontitis, polycystic ovarian syndrome, neurodegeneration, cancer …

M Ala, M Ala - ACS pharmacology & translational science, 2021 - ACS Publications
Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Myeloid-derived suppressor cells function as novel osteoclast progenitors enhancing bone loss in breast cancer

A Sawant, J Deshane, J Jules, CM Lee, BA Harris… - Cancer research, 2013 - AACR
Enhanced bone destruction is a hallmark of various carcinomas such as breast cancer,
where osteolytic bone metastasis is associated with increased morbidity and mortality …

Contribution of statins towards periodontal treatment: a review

C Petit, F Batool, IM Bugueno, P Schwinté… - Mediators of …, 2019 - Wiley Online Library
The pleiotropic effects of statins have been evaluated to assess their potential benefit in the
treatment of various inflammatory and immune‐mediated diseases including periodontitis …

Topical treatment with probiotic Lactobacillus brevis CD2 inhibits experimental periodontal inflammation and bone loss

T Maekawa, G Hajishengallis - Journal of periodontal research, 2014 - Wiley Online Library
Background and Objective An increasing body of evidence suggests that the use of probiotic
bacteria is a promising intervention approach for the treatment of inflammatory diseases with …

Severe magnesium deficiency compromises systemic bone mineral density and aggravates inflammatory bone resorption

MM Belluci, RS de Molon, C Rossa Jr, S Tetradis… - The Journal of …, 2020 - Elsevier
We sought to evaluate the effects of magnesium (Mg) intake deficiency on bone metabolism
in rats with induced periodontal disease (PD). Holtzman rats were randomly divided into two …

Role of nitric oxide in type 1 diabetes-induced osteoporosis

S Jeddi, N Yousefzadeh, K Kashfi, A Ghasemi - Biochemical Pharmacology, 2022 - Elsevier
Abstract Type 1 diabetes (T1D)-induced osteoporosis is characterized by decreased bone
mineral density, bone quality, rate of bone healing, bone formation, and increased bone …

Association between periodontitis and osteoporosis in United States adults from the National Health and Nutrition Examination Survey: a cross-sectional analysis

J Peng, J Chen, Y Liu, J Lyu, B Zhang - BMC Oral Health, 2023 - Springer
Objective This cross-sectional study aimed to investigate the association between
periodontitis and osteoporosis among US adults as well as the subgroup of menopausal …

Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and …

DZ Li, QX Zhang, XX Dong, HD Li, X Ma - Journal of Bone and Mineral …, 2014 - Springer
The bone protective effects of the hydrogen molecule (H 2) have been demonstrated in
several osteoporosis models while the underlying molecular mechanism has remained …

Periodontitis and redox status: a review

L Nibali, N Donos - Current pharmaceutical design, 2013 - ingentaconnect.com
Periodontal diseases are common inflammatory conditions of the supporting apparatus of
the teeth which lead to early tooth loss. This review discusses the evidence for a role of …