[HTML][HTML] Hepatitis E virus: Epidemiology, diagnosis, clinical manifestations, and treatment

AT Aslan, HY Balaban - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
The hepatitis E virus (HEV) is the fifth known form of viral hepatitis and was first recognized
as the cause of an epidemic of unexplained acute hepatitis in the early 1980s. Globally, it is …

Laboratory challenges in the diagnosis of hepatitis E virus

DW Al-Sadeq, AF Majdalawieh… - Journal of Medical …, 2018 - microbiologyresearch.org
Hepatitis E virus (HEV) is an RNA virus that is an important cause of both acute and chronic
hepatitis worldwide. To date, there are eight HEV genotypes that can infect mammals. HEV …

EASL Clinical Practice Guidelines on hepatitis E virus infection

HR Dalton, N Kamar, SA Baylis, D Moradpour… - Journal of …, 2018 - Elsevier
Infection with hepatitis E virus (HEV) is a significant cause of morbidity and mortality,
representing an important global health problem. Our understanding of HEV has changed …

Hepatitis E virus lifecycle and identification of 3 forms of the ORF2 capsid protein

C Montpellier, C Wychowski, IM Sayed, JC Meunier… - Gastroenterology, 2018 - Elsevier
Background & Aims Hepatitis E virus (HEV) infection is a major cause of acute hepatitis
worldwide. Approximately 2 billion people live in areas endemic for HEV and are at risk of …

Origin, antigenicity, and function of a secreted form of ORF2 in hepatitis E virus infection

X Yin, D Ying, S Lhomme, Z Tang… - Proceedings of the …, 2018 - National Acad Sciences
The enterically transmitted hepatitis E virus (HEV) adopts a unique strategy to exit cells by
cloaking its capsid (encoded by the viral ORF2 gene) and circulating in the blood as “quasi …

Transmission and epidemiology of hepatitis E virus genotype 3 and 4 infections

HR Dalton, J Izopet - Cold Spring Harbor …, 2018 - perspectivesinmedicine.cshlp.org
Following the introduction of robust serological and molecular tools, our understanding of
the epidemiology of zoonotic hepatitis E virus (HEV) has improved considerably in recent …

[HTML][HTML] Hepatitis E in immunocompromised individuals

K Damiris, MA Meybodi, M Niazi… - World journal of …, 2022 - ncbi.nlm.nih.gov
Hepatitis E virus (HEV) originally identified as a cause of acute icteric hepatitis in developing
countries has grown to be a cause of zoonotic viral hepatitis in developed countries such as …

HEV ORF2 protein-antibody complex deposits are associated with glomerulonephritis in hepatitis E with reduced immune status

AL Leblond, B Helmchen, M Ankavay… - Nature …, 2024 - nature.com
Hepatitis E virus (HEV) infection, one of the most common forms of hepatitis worldwide, is
often associated with extrahepatic, particularly renal, manifestations. However, the …

A ribavirin-induced ORF2 single-nucleotide variant produces defective hepatitis E virus particles with immune decoy function

TL Meister, Y Brüggemann, MK Nocke… - Proceedings of the …, 2022 - National Acad Sciences
Hepatitis E virus (HEV) is the causative agent of hepatitis E in humans and is the leading
cause of enterically transmitted viral hepatitis worldwide. Ribavirin (RBV) is currently the …

Soluble ORF2 protein enhances HEV replication and induces long-lasting antibody response and protective immunity in vivo

P Ralfs, B Holland, E Salinas, B Bremer, M Wang… - Hepatology, 2023 - journals.lww.com
Soluble ORF2 protein enhances HEV replication and induces lo... : Hepatology Soluble ORF2
protein enhances HEV replication and induces long-lasting antibody response and protective …