Many diseases, such as inflammatory and central nervous system disorders, currently have
a limited number of effective side-effect free treatments. Citronellol (CT) is a monoterpene …

The widespread use of antibiotics, especially those with a broad spectrum of activity, has
resulted in the development of multidrug resistance in many strains of bacteria, including …

Recent efforts in biological engineering have made detection of nucleic acids in samples
more rapid, inexpensive and sensitive using CRISPR-based approaches. We expand one of …

The increasing antibiotic resistance evolved by Helicobacter pylori has alarmingly reduced
the eradication rates of first-line therapies. To overcome the current circulating resistome, we …

Since the discovery of penicillin in the first half of the last century, antibiotics have become
the pillars of modern medicine for fighting bacterial infections. However, pathogens resistant …

Two-component regulatory systems (TCRS) are ubiquitous signal transduction mechanisms
evolved by bacteria for sensing and adapting to the constant changes that occur in their …

HP1043 is an essential orphan response regulator of Helicobacter pylori orchestrating
multiple crucial cellular processes. Classified as a member of the OmpR/PhoB family of two …

Helicobacter pylori is considered the most prevalent bacterial pathogen in humans. The
increasing antibiotic resistance evolved by this microorganism has raised alarm bells …

Background: Identification of novel Ure inhibitors with high potency has received
considerable attention. Methodology & results: Ure inhibition was determined using the …

Vibrio parahaemolyticus is a significant seafood-borne enteropathogen with a global
concern. Its propensity for biofilm formation has increased capacity for seafood …