The Role of l-Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation

MA Virmani, M Cirulli - International journal of molecular sciences, 2022 - mdpi.com
Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …

The mutual interplay of gut microbiota, diet and human disease

P Illiano, R Brambilla, C Parolini - The FEBS journal, 2020 - Wiley Online Library
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

[HTML][HTML] Carnitine transport and fatty acid oxidation

N Longo, M Frigeni, M Pasquali - … et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
Carnitine is essential for the transfer of long-chain fatty acids across the inner mitochondrial
membrane for subsequent β-oxidation. It can be synthesized by the body or assumed with …

Organic cation transporters in health and disease

H Koepsell - Pharmacological reviews, 2020 - ASPET
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

The biochemistry and physiology of mitochondrial fatty acid β-oxidation and its genetic disorders

SM Houten, S Violante, FV Ventura… - Annual review of …, 2016 - annualreviews.org
Mitochondrial fatty acid β-oxidation (FAO) is the major pathway for the degradation of fatty
acids and is essential for maintaining energy homeostasis in the human body. Fatty acids …

[图书][B] Principles of animal nutrition

G Wu - 2017 - taylorfrancis.com
Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Catalytic mechanisms of Fe (II)-and 2-oxoglutarate-dependent oxygenases

S Martinez, RP Hausinger - Journal of Biological Chemistry, 2015 - ASBMB
Mononuclear non-heme Fe (II)-and 2-oxoglutarate (2OG)-dependent oxygenases comprise
a large family of enzymes that utilize an Fe (IV)-oxo intermediate to initiate diverse oxidative …

Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease

E Horgusluoglu, R Neff, WM Song… - Alzheimer's & …, 2022 - Wiley Online Library
Metabolites, the biochemical products of the cellular process, can be used to measure
alterations in biochemical pathways related to the pathogenesis of Alzheimer's disease …

Acylcarnitines: reflecting or inflicting insulin resistance?

MG Schooneman, FM Vaz, SM Houten, MR Soeters - Diabetes, 2013 - Am Diabetes Assoc
The incidence of obesity and insulin resistance is growing, and the increase in type 2
diabetes mel-litus (DM2) constitutes one of the biggest challenges for our healthcare …