Gold nanomaterial engineering for macrophage‐mediated inflammation and tumor treatment

W Chen, F Zhang, Y Ju, J Hong… - Advanced Healthcare …, 2021 - Wiley Online Library
Macrophages play an important role in the body's immune defense process. Phenotype
imbalance between M1 and M2 macrophages induced by inflammation‐related disorders …

Nanomedicine in diagnostics and therapy of cardiovascular diseases: Beyond atherosclerotic plaque imaging

I Cicha, S Lyer, C Alexiou, CD Garlichs - Nanotechnology Reviews, 2013 - degruyter.com
Atherosclerosis results from the accumulation of the modified lipoproteins within the artery
walls, which triggers complex vascular inflammatory processes. Although the pharmacologic …

Excretion and toxicity of gold–iron nanoparticles

JT Jenkins, DL Halaney, KV Sokolov, LL Ma… - … , Biology and Medicine, 2013 - Elsevier
Though gold nanoparticles have been considered bio-inert, recent studies have questioned
their safety. To reduce the potential for toxicity, we developed a nanoclustering of gold and …

Nano-systems for advanced therapeutics and diagnosis of atherosclerosis

C Gaurav, B Saurav, R Goutam… - Current Pharmaceutical …, 2015 - ingentaconnect.com
Cardiovascular diseases (CVDs) are the leading cause of death and morbidity worldwide.
Atherosclerotic situations such as acute myocardial infarction (MI) and stroke are still major …

Poly (aminoether)–gold Nanorod assemblies for shRNA plasmid-induced gene silencing

J Ramos, K Rege - Molecular pharmaceutics, 2013 - ACS Publications
Gold nanorods (GNRs) have emerged as promising nanomaterials for biosensing, imaging,
photothermal hyperthermia treatments, and therapeutic delivery for several diseases. We …

Cardiovascular therapy through nanotechnology–how far are we still from bedside?

I Cicha, CD Garlichs, C Alexiou - European Journal of Nanomedicine, 2014 - degruyter.com
Recent years brought about a widespread interest in the potential applications of
nanotechnology for the diagnostics and the therapy of human diseases. With its promise of …

Atherosclerosis and nanomedicine potential: current advances and future opportunities

F Jiang, Y Zhu, C Gong, X Wei - Current Medicinal Chemistry, 2020 - ingentaconnect.com
Atherosclerosis is the leading inducement of cardiovascular diseases, which ranks the first
cause of global deaths. It is an arterial disease associated with dyslipidemia and changes in …

Dual-modality fiber-based OCT-TPL imaging system for simultaneous microstructural and molecular analysis of atherosclerotic plaques

T Wang, A McElroy, D Halaney, D Vela… - Biomedical optics …, 2015 - opg.optica.org
New optical imaging techniques that provide contrast to study both the anatomy and
composition of atherosclerotic plaques can be utilized to better understand the formation …

Phase-sensitive OCT imaging of multiple nanoparticle species using spectrally multiplexed single pulse photothermal excitation

S Kim, MT Rinehart, H Park, Y Zhu… - Biomedical Optics Express, 2012 - opg.optica.org
We apply phase-sensitive optical coherence tomography to image multiple nanoparticle
species with two excitation wavelengths matched to their distinct absorption peaks. Using …

Interactions of composite gold nanoparticles with cells and tissue: implications in clinical translation for cancer imaging and therapy

JO Tam - 2012 - repositories.lib.utexas.edu
Current methods to diagnose and treat cancer often involve expensive, time-consuming
equipment and materials that may lead to unwanted side effects and may not even increase …