The complexities and challenges of preventing and treating nontuberculous mycobacterial diseases

SL Baldwin, SE Larsen, D Ordway… - PLoS neglected …, 2019 - journals.plos.org
Seemingly innocuous nontuberculous mycobacteria (NTM) species, classified by their slow
or rapid growth rates, can cause a wide range of illnesses, from skin ulceration to severe …

Dissemination of Mycobacterium abscessus via global transmission networks

C Ruis, JM Bryant, SC Bell, R Thomson… - Nature …, 2021 - nature.com
Mycobacterium abscessus, a multidrug-resistant nontuberculous mycobacterium, has
emerged as a major pathogen affecting people with cystic fibrosis (CF). Although originally …

A Closer Look at the Genomic Variation of Geographically Diverse Mycobacterium abscessus Clones That Cause Human Infection and Disease

RM Davidson - Frontiers in Microbiology, 2018 - frontiersin.org
Mycobacterium abscessus is a multidrug resistant bacterium that causes pulmonary and
extrapulmonary disease. The reported prevalence of pulmonary M. abscessus infections …

Population Genomics of Mycobacterium abscessus from US Cystic Fibrosis Care Centers

RM Davidson, NA Hasan, LE Epperson… - Annals of the …, 2021 - atsjournals.org
Rationale: Mycobacterium abscessus is a significant threat to individuals with cystic fibrosis
(CF) because of innate drug resistance and potential transmission between patients. Recent …

Cross-transmission Is Not the Source of New Mycobacterium abscessus Infections in a Multicenter Cohort of Cystic Fibrosis Patients

RM Doyle, M Rubio, G Dixon, J Hartley… - Clinical infectious …, 2020 - academic.oup.com
Background Mycobacterium abscessus is an extensively drug–resistant pathogen that
causes pulmonary disease, particularly in cystic fibrosis (CF) patients. Identifying direct …

Advancing translational science for pulmonary nontuberculous mycobacterial infections. A road map for research

S Daniel-Wayman, G Abate, DL Barber… - American journal of …, 2019 - atsjournals.org
Nontuberculous mycobacterial pulmonary disease (NTM PD) may be chronic, requiring
lengthy and complex regimens over many months to years. After treatment, patients are …

Genome sequencing of Mycobacterium abscessus isolates from patients in the United States and comparisons to globally diverse clinical strains

RM Davidson, NA Hasan, PR Reynolds… - Journal of clinical …, 2014 - Am Soc Microbiol
Nontuberculous mycobacterial infections caused by Mycobacterium abscessus are
responsible for a range of disease manifestations from pulmonary to skin infections and are …

Genomic characterization of sporadic isolates of the dominant clone of Mycobacterium abscessus subspecies massiliense

RM Davidson, JB Benoit, SM Kammlade, NA Hasan… - Scientific reports, 2021 - nature.com
Recent studies have characterized a dominant clone (Clone 1) of Mycobacterium abscessus
subspecies massiliense (M. massiliense) associated with high prevalence in cystic fibrosis …

Nontuberculous mycobacteria in cystic fibrosis: updates and the path forward

SL Martiniano, RM Davidson, JA Nick - Pediatric pulmonology, 2017 - Wiley Online Library
Nontuberculous mycobacteria (NTM) are troublesome pathogens that can cause significant
pulmonary disease in patients with cystic fibrosis (CF). Diagnosis can be difficult in the …

Genomic analysis of a hospital-associated outbreak of Mycobacterium abscessus: implications on transmission

RM Davidson, SE Nick, SM Kammlade… - Journal of clinical …, 2022 - Am Soc Microbiol
Whole-genome sequencing (WGS) has recently been used to investigate acquisition of
Mycobacterium abscessus. Investigators have reached conflicting conclusions about the …