Oxidation and deamidation of monoclonal antibody products: potential impact on stability, biological activity, and efficacy
The role in human health of therapeutic proteins in general, and monoclonal antibodies
(mAbs) in particular, has been significant and is continuously evolving. A considerable …
(mAbs) in particular, has been significant and is continuously evolving. A considerable …
Analytical techniques for the characterization and quantification of monoclonal antibodies
HA Alhazmi, M Albratty - Pharmaceuticals, 2023 - mdpi.com
Monoclonal antibodies (mAbs) are a fast-growing class of biopharmaceuticals. They are
widely used in the identification and detection of cell makers, serum analytes, and …
widely used in the identification and detection of cell makers, serum analytes, and …
Applications of capillary electromigration methods for separation and analysis of proteins (2017–mid 2021)–a review
S Štěpánová, V Kašička - Analytica Chimica Acta, 2022 - Elsevier
This paper provides a detailed overview of relevant developments in separation and
analysis of proteins by capillary electromigration (CE) methods in the period 2017–mid …
analysis of proteins by capillary electromigration (CE) methods in the period 2017–mid …
Recent trends of capillary electrophoresis‐mass spectrometry in proteomics research
FP Gomes, JR Yates III - Mass spectrometry reviews, 2019 - Wiley Online Library
Progress in proteomics research has led to a demand for powerful analytical tools with high
separation efficiency and sensitivity for confident identification and quantification of proteins …
separation efficiency and sensitivity for confident identification and quantification of proteins …
Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches
Accelerated development of new therapeutics in an increasingly competitive landscape
requires the use of high throughput analytical platforms. In addition, the complexity of novel …
requires the use of high throughput analytical platforms. In addition, the complexity of novel …
Monitoring of immunoglobulin N- and O-glycosylation in health and disease
Protein N-and O-glycosylation are well known co-and post-translational modifications of
immunoglobulins. Antibody glycosylation on the Fab and Fc portion is known to influence …
immunoglobulins. Antibody glycosylation on the Fab and Fc portion is known to influence …
Capillary electrophoresis‐mass spectrometry for intact protein analysis: Pharmaceutical and biomedical applications (2018–March 2023)
K Maráková, M Opetová… - Journal of Separation …, 2023 - Wiley Online Library
Capillary electrophoresis is recognized as a valued separation technique for its high
separation efficiency, low sample consumption, good economic and ecological aspects …
separation efficiency, low sample consumption, good economic and ecological aspects …
Analytical similarity assessment of biosimilars: global regulatory landscape, recent studies and major advancements in orthogonal platforms
Biopharmaceuticals are one of the fastest-growing sectors in the biotechnology industry.
Within the umbrella of biopharmaceuticals, the biosimilar segment is expanding with …
Within the umbrella of biopharmaceuticals, the biosimilar segment is expanding with …
Insights from capillary electrophoresis approaches for characterization of monoclonal antibodies and antibody drug conjugates in the period 2016–2018
Monoclonal antibodies (mAbs) and their related products as antibody-drug-conjugates
(ADCs) or biosimilars represent a constantly growing class of molecules therapeutic proteins …
(ADCs) or biosimilars represent a constantly growing class of molecules therapeutic proteins …
Challenging bioanalyses with capillary electrophoresis
This report covers advances in capillary electrophoresis (CE) from January 2018 through
September 2019. A summary of the literature during this time period is insightful. A search …
September 2019. A summary of the literature during this time period is insightful. A search …