This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Drug overdoses from opioids and stimulants are a major cause of mortality in the United
States. It is unclear if there are stable sex differences in overdose mortality for these drugs …

Continuous glucose monitoring (CGM) has become a widely used tool in the ambulatory
setting for monitoring glucose levels, as well as detecting uncontrolled hyperglycemia …

Obesity hypoventilation syndrome (OHS) is considered as a diagnosis in obese patients
(body mass index [BMI]≥ 30 kg/m 2) who also have sleep-disordered breathing and awake …

Respiratory depression is the proximal cause of death in opioid overdose, yet the
mechanisms underlying this potentially fatal outcome are not well understood. The goal of …

Despite current advances in acute postoperative pain management, prevalence remains
high. Inadequate treatment could lead to poor outcomes and even progression to chronic …

Abstract Background and Objective Opioid-induced respiratory depression (OIRD) is a
potentially fatal complication associated with conventional opioids. Currently, there is a …

Background Opioid-induced respiratory depression is common on the general care floor.
However, the clinical and economic burden of respiratory depression is not well-described …

Background: Balancing between opioid analgesia and respiratory depression continues to
challenge clinicians in perioperative, emergency department and other acute care settings …

Study objective Opioid administration for pain in general care floor patients remains
common, and can lead to adverse outcomes, including respiratory compromise. The …