Introduced in the late 1950s, polyenes represent the oldest family of antifungal drugs. The
discovery of amphotericin B and its therapeutic uses is considered one of the most important …

Abstract Liposomal amphotericin B (AmBisome®; LAmB) is a unique lipid formulation of
amphotericin B. LAmB is a standard of care for a wide range of medically important …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Abstract These European Society for Clinical Microbiology and Infectious Diseases and
European Confederation of Medical Mycology Joint Clinical Guidelines focus on the …

This review discusses important advances in fungal diagnostics and in the antifungal
armamentarium as applied to aspergillus species. Recent insights concerning host defenses …

The introduction of new antifungal agents (eg, echinocandins, second-generation triazoles)
in the past decade has transformed the management of invasive mycoses to the point that …

Scope Presenting symptoms, distributions and patterns of diseases and vulnerability to
invasive aspergillosis (IA) are similar between children and adults. However, differences …

Clin Microbiol Infect 2012; 18 (Suppl. 7): 38–52 Abstract Invasive candidiasis (IC) is a
relatively common syndrome in neonates and children and is associated with significant …

The successful management of invasive fungal infections continues to pose a difficult
challenge to clinicians. As the population of at-risk immunocompromised patients increases …