Instrumentation at the leading edge of proteomics

TM Peters-Clarke, JJ Coon, NM Riley - Analytical Chemistry, 2024 - ACS Publications
The proteome, or collection of proteoforms expressed in a biological system, is dynamic and
heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have …

Parallelized acquisition of orbitrap and astral analyzers enables high-throughput quantitative analysis

HI Stewart, D Grinfeld, A Giannakopulos… - Analytical …, 2023 - ACS Publications
The growing trend toward high-throughput proteomics demands rapid liquid
chromatography–mass spectrometry (LC–MS) cycles that limit the available time to gather …

LC-Q-TOF-MS/MS detection of food flavonoids: Principle, methodology, and applications

M Yang, J Li, C Zhao, H Xiao, X Fang… - CritiCal reviews in Food …, 2023 - Taylor & Francis
Flavonoids have been attracting increasing research interest because of their multiple
health promoting effects. However, many flavonoids with similar structures are present in …

Single-cell ICP-MS to address the role of trace elements at a cellular level

ABS da Silva, MAZ Arruda - Journal of Trace Elements in Medicine and …, 2023 - Elsevier
The heterogeneity properties shown by cells or unicellular organisms have led to the
development of analytical methods at the single-cell level. In this sense, considering the …

Coupling online size exclusion chromatography with charge detection-mass spectrometry using Hadamard transform multiplexing

JD Sanders, ON Owen, BH Tran… - Analytical …, 2024 - ACS Publications
Charge detection mass spectrometry (CD-MS) is a powerful technique for the analysis of
large, heterogeneous biomolecules. By directly measuring the charge states of individual …

Applications of mass spectrometry in cosmetic analysis: An overview

Y Shang, X Meng, J Liu, N Song, H Zheng… - … of Chromatography A, 2023 - Elsevier
Mass spectrometry (MS) is a crucial tool in cosmetic analysis. It is widely used for ingredient
screening, quality control, risk monitoring, authenticity verification, and efficacy evaluation …

In-Line Thermal Desorption and Dielectric Barrier Discharge Ionization for Rapid Mass Spectrometry Detection of Explosives

TP Forbes, EL Robinson, E Sisco, A Koss - Analytical Chemistry, 2024 - ACS Publications
Thermal desorption (TD) of wipe-based samples was coupled with an in-line dielectric
barrier discharge ionization (DBDI) source and rugged compact time-of-flight mass …

Recent progress in analytical strategies of arsenic-binding proteomes in living systems

J Liu, B Chen, R Zhang, Y Li, R Chen, S Zhu… - Analytical and …, 2023 - Springer
Arsenic (As) is one of the most concerning elements due to its high exposure risks to
organisms and ecosystems. The interaction between arsenicals and proteins plays a pivotal …

Food metabolomics: Latest hardware—Developments for nontargeted food authenticity and food safety testing

M Creydt, M Fischer - Electrophoresis, 2022 - Wiley Online Library
The analytical requirements for food testing have increased significantly in recent years. On
the one hand, because food fraud is becoming an ever‐greater challenge worldwide, and …

Isomer analysis by mass spectrometry in clinical science

T Furuhashi, W Weckwerth - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Isomeric compounds are present in the human body as well as in drugs and exhibit different
physiological functions, making their measurement important in clinical science. Isomer …