Fatty acid–binding proteins (FABPs) are small lipid-binding proteins abundantly expressed
in tissues that are highly active in fatty acid (FA) metabolism. Ten mammalian FABPs have …

Lipid transfer proteins (LTPs) are crucial players in nonvesicular lipid trafficking. LTPs
sharing a lipocalin lipid transfer domain (lipocalin-like proteins) have a wide range of …

Introduction Aging is characterized by progressive metabolic dyshomeostasis that increases
morbidity and mortality. Solutions for optimizing healthy aging are challenged by lacking …

Fatty-acid binding protein 4 (FABP4) is an essential driver for the progression of metabolic-
related inflammatory diseases including obesity, diabetes, atherosclerosis, and various lipid …

Three isonitrogenous diets (41% crude protein) with 4.87%, 10.75% and 16.10% lipid were
designed to evaluate the effects of dietary lipid levels growth, antioxidant capacity …

Ordinary small molecule de novo drug design is time-consuming and expensive. Recently,
computational tools were employed and proved their efficacy in accelerating the overall drug …

Abstract Purpose of Review Fatty acid-binding protein 4 (FABP4) plays a role in lipid
metabolism and cardiovascular health. In this paper, we cover FABP4 biology, its …

Although multiple approaches for characterizing protein–ligand interactions are available in
target-based drug discovery, their throughput for determining selectivity is quite limited …

The optimal dietary lipid requirement and underlying lipid metabolic mechanisms remain
elusive in greasyback shrimp (Metapenaeus ensis), presenting significant obstacles to the …

Reperfusion therapy is currently the most effective treatment for acute ischemic stroke, but
often results in secondary brain injury. Adipocyte fatty acid-binding protein (A-FABP, FABP4 …