Autophagy in kidney homeostasis and disease

C Tang, MJ Livingston, Z Liu, Z Dong - Nature Reviews Nephrology, 2020 - nature.com
Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic
components. Basal autophagy in kidney cells is essential for the maintenance of kidney …

Mechanism and medical implications of mammalian autophagy

I Dikic, Z Elazar - Nature reviews Molecular cell biology, 2018 - nature.com
Autophagy is a highly conserved catabolic process induced under various conditions of
cellular stress, which prevents cell damage and promotes survival in the event of energy or …

[HTML][HTML] NF-κB signaling in inflammation

T Liu, L Zhang, D Joo, SC Sun - Signal transduction and targeted …, 2017 - nature.com
The transcription factor NF-κB regulates multiple aspects of innate and adaptive immune
functions and serves as a pivotal mediator of inflammatory responses. NF-κB induces the …

[HTML][HTML] Roles of autophagy in oxidative stress

HR Yun, YH Jo, J Kim, Y Shin, SS Kim… - International journal of …, 2020 - mdpi.com
Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by
lysosomal degradation pathways. Autophagy is implicated in various biological processes …

[HTML][HTML] Life, death, and autophagy in cancer: NF-κB turns up everywhere

D Verzella, A Pescatore, D Capece, D Vecchiotti… - Cell death & …, 2020 - nature.com
Escaping programmed cell death is a hallmark of cancer. NF-κB transcription factors are key
regulator of cell survival and aberrant NF-κB signaling has been involved in the …

[HTML][HTML] NF-κB restricts inflammasome activation via elimination of damaged mitochondria

Z Zhong, A Umemura, E Sanchez-Lopez, S Liang… - Cell, 2016 - cell.com
Nuclear factor κB (NF-κB), a key activator of inflammation, primes the NLRP3-inflammasome
for activation by inducing pro-IL-1β and NLRP3 expression. NF-κB, however, also prevents …

[HTML][HTML] Resolution of inflammation: what controls its onset?

MA Sugimoto, LP Sousa, V Pinho, M Perretti… - Frontiers in …, 2016 - frontiersin.org
An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

[HTML][HTML] Autophagy in cancer metastasis

EE Mowers, MN Sharifi, KF Macleod - Oncogene, 2017 - nature.com
Autophagy is a highly conserved self-degradative process that has a key role in cellular
stress responses and survival. Recent work has begun to explore the function of autophagy …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

PAMP s and DAMP s: Signal 0s that spur autophagy and immunity

D Tang, R Kang, CB Coyne, HJ Zeh… - Immunological …, 2012 - Wiley Online Library
Pathogen‐associated molecular pattern molecules (PAMP s) are derived from
microorganisms and recognized by pattern recognition receptor (PRR)‐bearing cells of the …