Background Growing evidence points to a link between specific fatty acids ingested through
the diet and human health. Chain length, saturation degree, and position of double bonds in …

Studies over several decades have documented the beneficial actions of n-3
polyunsaturated fatty acids (PUFAs), which are plentiful in fish oil, in different disease states …

Background Stargardt disease (STGD1) is an autosomal recessive retinal dystrophy due to
mutations in ABCA4, characterized by subretinal deposition of lipofuscin-like substances …

Alzheimer disease (AD) is the most prevalent cause of dementia in the elderly. Although
impaired cognition and memory are the most prominent features of AD, abnormalities in …

Autosomal recessive Stargardt disease (STGD1) is an inherited retinal degenerative
disease associated with a mutated ATP-binding cassette, subfamily A, member 4 (ABCA4) …

Cytochrome P450 (CYP) gene mutations are a common predisposition associated with
glaucoma. Although the molecular mechanisms are largely unknown, omega-3 …

Although decreased retinal docosahexaenoic acid (DHA) is a known risk factor for
retinopathy, currently available omega-3 fatty acid supplements, which are absorbed as …

The purpose of this study was to evaluate the neuroprotective effects of omega-3
polyunsaturated fatty acid (ω3-PUFA) supplementation in a mouse model of OPA1 …

Diabetes mellitus has been a major cause of concern for the past few decades. As the
number of diabetic patients increases, so too does the occurrence of its complications …

Neonatal sepsis is a major cause of childhood mortality. Limited diagnostic tools and
mechanistic insights have hampered our abilities to develop prophylactic or therapeutic …