Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms

AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Organocatalytic activation of hydrogen peroxide: towards green and sustainable oxidations

ET Poursaitidis, PL Gkizis, I Triandafillidi… - Chemical …, 2024 - pubs.rsc.org
The advent of organocatalysis provided an additional option in every researcher's arsenal,
towards the development of elegant and sustainable protocols for various organic …

Negishi cross-couplings in the synthesis of amino acids

WDG Brittain, SL Cobb - Organic & Biomolecular Chemistry, 2018 - pubs.rsc.org
The Negishi cross-coupling is a powerful C–C bond-forming reaction widely utilised in many
areas of organic synthesis. This review details the use of Negishi cross-couplings in the …

Dioxiranes: a half-century journey

TH El-Assaad, J Zhu, A Sebastian… - Organic Chemistry …, 2022 - pubs.rsc.org
Dioxiranes are multi-tasking reagents with mild and selective oxygen transfer attributes.
These oxidants are accessed from the reaction of ketones with an oxidant and are employed …

[HTML][HTML] Synthesis of complex unnatural fluorine-containing amino acids

WDG Brittain, CM Lloyd, SL Cobb - Journal of Fluorine Chemistry, 2020 - Elsevier
The area of fluorinated amino acid synthesis has seen rapid growth over the past decade.
As reports of singly fluorinated natural amino acid derivatives have grown, researchers have …

Enantioselective total synthesis of (+)-arboridinine

Z Zhang, S Xie, B Cheng, H Zhai… - Journal of the American …, 2019 - ACS Publications
The enantioselective total synthesis of cage-shaped alkaloid (+)-arboridinine is reported.
The synthesis takes advantage of the stereoselective double-Mannich reaction to rapidly …

A Visible‐Light‐Driven Molecular Motor Based on Pyrene

D Roke, BL Feringa, SJ Wezenberg - Helvetica Chimica Acta, 2019 - Wiley Online Library
The aromatic core of an overcrowded alkene‐based molecular motor is extended with the
goal of inducing isomerization with visible light instead of harmful UV light. In our design, the …

Highly diastereoselective metal-free catalytic synthesis of drug-like spiroimidazolidinone

AM Jassem, AH Raheemah, WA Radhi, AM Alid… - Russian Journal of …, 2019 - Springer
A four-step procedure has been developed for the synthesis of (S)-3-isopropyl-1-[(R)-1-
phenylethyl)-1, 4-diazaspiro [4.5] decan-2-one with high diastereoselectivity (up to 95% de) …

Recent developments in the chemistry of Negishi coupling: a review

Muzammil, AF Zahoor, B Parveen, S Javed, R Akhtar… - Chemical Papers, 2024 - Springer
Negishi cross-coupling reaction is a familiar reaction for the formation of carbon–carbon
bonds that couples organic halides or triflates with organozinc compounds. Palladium is …

Dioxirane‐Based Stereoselective and Oxidative Transformations

I Neogi, KN Parida - ChemistrySelect, 2024 - Wiley Online Library
The synthesis of chiral organic molecules is a purity‐driven research that has become an
essential part of our lives due to their applications in pharmaceuticals. Contemporary …