Advances in organ-on-a-chip materials and devices

BK Nahak, A Mishra, S Preetam… - ACS applied bio …, 2022 - ACS Publications
The organ-on-a-chip (OoC) paves a way for biomedical applications ranging from preclinical
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …

[HTML][HTML] CRISPR-microfluidics nexus: Advancing biomedical applications for understanding and detection

ZS Razavi, M Soltani, H Pazoki-Toroudi… - Sensors and Actuators A …, 2024 - Elsevier
The integration of CRISPR technology with microfluidic-based biosensors has greatly
expanded its applications in medicine and molecular biology. This combination offers …

Reviewing methods of deep learning for diagnosing COVID-19, its variants and synergistic medicine combinations

Q Rafique, A Rehman, MS Afghan, HM Ahmad… - Computers in Biology …, 2023 - Elsevier
The COVID-19 pandemic has necessitated the development of reliable diagnostic methods
for accurately detecting the novel coronavirus and its variants. Deep learning (DL) …

Recent Advances in CRISPR/Cas9 Delivery Approaches for Therapeutic Gene Editing of Stem Cells

M Lotfi, D Morshedi Rad, SS Mashhadi… - Stem cell reviews and …, 2023 - Springer
Rapid advancement in genome editing technologies has provided new promises for treating
neoplasia, cardiovascular, neurodegenerative, and monogenic disorders. Recently, the …

[HTML][HTML] Progress in paper-based analytical devices for climate neutral biosensing

A Mishra, S Patra, V Srivastava, L Uzun… - … and Bioelectronics: X, 2022 - Elsevier
Disposable diagnostics is ramping up the development of green practices for healthcare.
Paper is an excellent natural substrate for emerging low-cost, ecologically acceptable …

CRISPR-powered microfluidics in diagnostics: a review of main applications

M Azimzadeh, M Mousazadeh, A Jahangiri-Manesh… - Chemosensors, 2021 - mdpi.com
In the past few years, the CRISPR (clustered regularly interspaced short palindromic
repeats) applications in medicine and molecular biology have broadened. CRISPR has also …

Advances and challenges of sensing in water using CRISPR-Cas technology

M Safarkhani, B Farasati Far, SH Kim… - ACS Biomaterials …, 2024 - ACS Publications
The groundbreaking gene-editing mechanism, CRISPR (Clustered Regularly Interspaced
Short Palindromic Repeats), paired with the protein Cas9, has significantly advanced the …

Stem cell therapy for COVID-19 pneumonia

MM Kebria, PB Milan, N Peyravian, J Kiani… - Molecular …, 2022 - Springer
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus is a highly
contagious microorganism, and despite substantial investigation, no progress has been …

Organ-on-a-chip: quo vademus? Applications and regulatory status

M Mendes, AS Morais, A Carlos, JJ Sousa… - Colloids and Surfaces B …, 2025 - Elsevier
Organ-on-a-chip systems, also referred to as microphysiological systems (MPS), represent
an advance in bioengineering microsystems designed to mimic key aspects of human organ …

[PDF][PDF] Dynamic three-dimensional cell-culture systems for enhanced in vitro applications

P Aishwarya, G Agrawal, J Sally, M Ravi - Curr. Sci, 2022 - researchgate.net
The advent of dynamic three-dimensional cell cultures has transformed the field of biological
research as they bridge the gap between in vitro and in vivo systems. 3D cell-culture …