Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

Macroautophagy (hereafter called autophagy) is a highly conserved physiological process
that degrades over-abundant or damaged organelles, large protein aggregates and …

The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Autophagy is an evolutionarily conserved lysosome-or vacuole-dependent catabolic
pathway in eukaryotes. Autophagy functions basally for cellular quality control and is …

In recent decades, the role of the peroxisome in physiology and disease conditions has
become increasingly important. Together with the mitochondria and other cellular …

Peroxisomes are metabolic organelles involved in lipid metabolism and cellular redox
balance. Peroxisomal function is central to fatty acid oxidation, ether phospholipid synthesis …

Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Reactive oxygen species (ROS) are highly reactive signaling molecules that maintain redox
homeostasis in mammalian cells. Dysregulation of redox homeostasis under pathological …

Stroke is a leading cause of mortality and morbidity worldwide. Understanding the
underlying mechanisms is important for developing effective therapies for treating stroke …

Noise overexposure causes oxidative stress, leading to auditory hair cell damage. Adaptive
peroxisome proliferation involving pejvakin, a peroxisome-associated protein from the …