Behavioural and psychological symptoms of dementia in mouse models of Alzheimer's disease-related pathology

F Kosel, JMS Pelley, TB Franklin - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Transgenic mouse models have been used extensively to model the cognitive impairments
arising from Alzheimer's disease (AD)-related pathology. However, less is known about the …

Rodent Models of Alzheimer's Disease: Past Misconceptions and Future Prospects

HM Collins, S Greenfield - International Journal of Molecular Sciences, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease with no effective
treatments, not least due to the lack of authentic animal models. Typically, rodent models …

Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain

S Ferreira, KA Pitman, S Wang… - Journal of …, 2020 - Wiley Online Library
In Alzheimer's disease, amyloid plaque formation is associated with the focal death of
oligodendrocytes and soluble amyloid β impairs the survival of oligodendrocytes in vitro …

Sleep and diurnal rest-activity rhythm disturbances in a mouse model of Alzheimer's disease

MJ Filon, E Wallace, S Wright, DJ Douglas… - Sleep, 2020 - academic.oup.com
Abstract Study Objectives Accumulating evidence suggests a strong association between
sleep, amyloid-beta (Aβ) deposition, and Alzheimer's disease (AD). We sought to determine …

The mRVG‐9R peptide as a potential therapeutic vector to the central nervous system cells

SA Villa‐Cedillo, A Soto‐Domínguez… - Cell Biology …, 2019 - Wiley Online Library
Our research group has developed a cell‐penetrating peptide‐based delivery system that
includes the Asn194Lys mutation in the rabies virus glycoprotein‐9R peptide (mRVG‐9R) …

The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain and affects presenilin-mediated gene regulation

F Oestereich, N Yousefpour, E Yang… - bioRxiv, 2020 - biorxiv.org
The cholesteryl ester transfer protein (CETP) is a lipid transfer protein responsible for the
exchange of cholesteryl esters and triglycerides between lipoproteins. Decreased CETP …

Identification of genetic risk factors for Parkinson's disease

A Illarionova - 2023 - ub01.uni-tuebingen.de
Parkinson's disease (PD) is a common progressive neurodegenerative disorder with a
complex and heterogeneous genetic landscape. Approximately 90% of all PD cases are …

Equidad según sexo y género en la investigación de la enfermedad de alzheimer

E Blázquez Corral - 2022 - diposit.ub.edu
[spa] A lo largo de los años, con la sobrerrepresentación de los hombres en las
investigaciones científicas, se han obtenido resultados y conocimientos sesgados …

Análisis de la eficiencia del péptido RVG29 mutante como vehículo para entrega de moléculas de DNA en cerebro murino.

SA Villa Cedillo - 2017 - eprints.uanl.mx
En los últimos años, se ha registrado un aumento en la esperanza de vida en la población
mundial, debido a esto la Organización Mundial de la Salud (OMS) ha declarado el …

[PDF][PDF] Novel Compatibility of Huanglianjiedu Decoction in Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease1

S Ma, X Wang, X Du, M Su, X Yao, J Shi - 2020 - scholar.archive.org
Background: Alzheimer's disease (AD) is characterized by progressive cognitive decline.
Behavioral and psychological symptoms in dementia (BPSD) are another critical …