Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …

Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …

We report identification of a novel genetic locus (GLC1P) for normal tension glaucoma
(NTG) on chromosome 12q14 using linkage studies of an African-American pedigree …

Epidemiological studies suggest that by 2020 the prevalence of primary open angle
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …

Glaucoma is a family of diseases whose pathology is defined by the progressive loss of
retinal ganglion cells. Clinically, glaucoma presents as a distinctive optic neuropathy with …

Background: Retinal ganglion cell (RGC) degeneration is a major feature of glaucoma
pathology. Neuroprotective approaches that delay or halt the progression of RGC loss are …

Intraocular pressure (IOP) reduction is currently the only evidence‐based treatment strategy
for glaucoma. However, IOP control in some individuals is challenging. Despite optimal …

Seemingly unaffected siblings of children with CYP1B1-related primary congenital/infantile
glaucoma should undergo genetic testing because of variable expressivity for the …

Glaucoma is a common, complex, heterogenous disease and it constitutes the major cause
of irreversible blindness worldwide. Primary open-angle glaucoma (POAG) is the most …

The authors indicate four key issues which, in their opinion, represent the most stimulating
challenges in the field of glaucoma today, and describe the present approaches and the …