This review concerns the synthesis and biological activities of pyrazino [1, 2-a] indoles and
pyrazino [1, 2-a] indol-1-ones reported since 1997 and the discovery of biological activity of …

In recent years, vinyl selenones were rediscovered as useful building blocks for new
synthetic transformations. This review will highlight these advances in the field of multiple …

A wide range of 3-selenylindoles were synthesized via an eco-friendly approach that uses
Oxone® as the oxidant in the presence of a catalytic amount of iodine. This mild and …

A three-component synthesis of novel spirooxindole-tetrahydropyrrolizines from secondary α-
aminoacids, isatins and vinyl selenones has been disclosed. Products were formed in good …

An atom-economical and practical method for the efficient synthesis of various pyrazino [1, 2-
a] indole-2-oxides was developed through a nickel (II)-catalyzed [5+ 1] annulation of 2 …

Dihydropyrrolo [1, 2-a] pyrazinone rings are a class of heterocycles present in a wide range
of bioactive natural products and analogues thereof. As a direct result of their bioactivity, the …

The synthesis of 2, 3-dihydropyrazino [1, 2-a] indol-4 (1H)-ones from the sequential reaction
of amino acid methyl esters with readily available indole-2-ylmethyl acetates is described …

A new protocol for the synthesis of N-vinyl azoles using vinyl selenones and azoles in the
presence of potassium hydroxide was developed. This reaction proceeded under mild and …

In the present paper, a novel series of pyrazino [1, 2-a] indole derivatives 6 (ak) were
synthesized by Ugi four-component reaction (U-4CR), followed by an intramolecular …

The first direct N-heterocyclic carbene (NHC)-catalyzed preparation of allylic amines bearing
a quaternary center (α-tertiary amine) from isatin-derived ketimines in the presence of vinyl …