Oxidative stress as a possible target in the treatment of toxoplasmosis: perspectives and ambiguities

K Szewczyk-Golec, M Pawłowska… - International journal of …, 2021 - mdpi.com
Toxoplasma gondii is an apicomplexan parasite causing toxoplasmosis, a common disease,
which is most typically asymptomatic. However, toxoplasmosis can be severe and even fatal …

Parasite and host erythrocyte kinomics of Plasmodium infection

J Adderley, T Williamson, C Doerig - Trends in Parasitology, 2021 - cell.com
Malaria remains a heavy public health and socioeconomic burden in tropical and
subtropical regions. Increasing resistance against front-line treatments implies that novel …

Indole: the after next scaffold of antiplasmodial agents?

AS Surur, SA Huluka, ML Mitku… - … Design, Development and …, 2020 - Taylor & Francis
Malaria remains a global public health problem due to the uphill fight against the causative
Plasmodium parasites that are relentless in developing resistance. Indole-based …

Melatonin: A look at protozoal and helminths

PIR Franco, JR do Carmo Neto, RO Guerra… - Biochimie, 2024 - Elsevier
Melatonin is a pleiotropic neurohormone found in different animal, plant, and microorganism
species. It is a product resulting from tryptophan metabolism in the pineal gland and is …

The knockout for G Protein-Coupled Receptor-Like PfSR25 increases the susceptibility of malaria parasites to the antimalarials lumefantrine and piperaquine but not …

BM Santos, BKM Dias, M Nakabashi… - Frontiers in …, 2021 - frontiersin.org
Previously we have reported that the G protein-coupled receptor (GPCR)-like PfSR25 in
Plasmodium falciparum is a potassium (K+) sensor linked to intracellular calcium signaling …

Melatonin attenuates dextran sodium sulfate induced colitis in obese mice

S Pan, F Hong, L Li, Y Guo, X Qiao, J Zhang, P Xu… - Pharmaceuticals, 2021 - mdpi.com
Epidemiological studies have indicated that obesity is an independent risk factor for colitis
and that a high-fat diet (HFD) increases the deterioration of colitis-related indicators in mice …

Role of Melatonin in Viral, Bacterial and Parasitic Infections

GJM Maestroni - Biomolecules, 2024 - mdpi.com
In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the
night's darkness hours. Its main function is synchronizing the organism in the photoperiod. In …

Molecular basis of synchronous replication of malaria parasites in the blood stage

BM Dos Santos, PHS Pereira, CRS Garcia - Current Opinion in …, 2021 - Elsevier
Highlights•Unraveling the mechanisms responsible for synchronizing the asexual cycle of
Plasmodium may be the key to fighting malaria.•The hormone melatonin produced by the …

[HTML][HTML] Antimalarial effect of synthetic endoperoxide on synchronized Plasmodium chabaudi infected mice

NSM Aly, H Matsumori, TQ Dinh, A Sato… - Parasites, Hosts and …, 2023 - ncbi.nlm.nih.gov
The discovery of new antimalarial drugs can be developed using asynchronized
Plasmodium berghei malaria parasites in vivo in mice. Studies on a particular stage are also …

Role of Melatonin in Viral, Bacterial and Parasitic Infections. Biomolecules 2024, 14, 356

GJM Maestroni - 2024 - europepmc.org
In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the
night's darkness hours. Its main function is synchronizing the organism in the photoperiod. In …