Anticancer potential of furanocoumarins: mechanistic and therapeutic aspects

S Ahmed, H Khan, M Aschner, H Mirzae… - International Journal of …, 2020 - mdpi.com
Cancer is one of the most extreme medical conditions in both developing and developed
countries around the world, causing millions of deaths each year. Chemotherapy and/or …

Anticancer potential of coumarin and its derivatives

N Bhattarai, AA Kumbhar, YR Pokharel… - Mini Reviews in …, 2021 - ingentaconnect.com
Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

[Retracted] Pharmacological Properties of Bergapten: Mechanistic and Therapeutic Aspects

MM Quetglas-Llabrés, C Quispe… - Oxidative medicine …, 2022 - Wiley Online Library
Bergapten (BP) or 5‐methoxypsoralen (5‐MOP) is a furocoumarin compound mainly found
in bergamot essential oil but also in other citrus essential oils and grapefruit juice. This …

Structure based multitargeted molecular docking analysis of selected furanocoumarins against breast cancer

R Acharya, S Chacko, P Bose, A Lapenna… - Scientific reports, 2019 - nature.com
Breast cancer is one of the biggest global dilemmas and its current therapy is to target the
hormone receptors by the use of partial agonists/antagonists. Potent drugs for breast cancer …

Bergapten: A review of its pharmacology, pharmacokinetics, and toxicity

Y Liang, L Xie, K Liu, Y Cao, X Dai… - Phytotherapy …, 2021 - Wiley Online Library
Bergapten is a natural furocoumarin, also known as 5‐methoxypsoralen, and its medicinal
value has been paid more and more attention. By sorting out the pharmacological literature …

Regulation and targeting of SREBP-1 in hepatocellular carcinoma

F Su, A Koeberle - Cancer and Metastasis Reviews, 2024 - Springer
Hepatocellular carcinoma (HCC) is an increasing burden on global public health and is
associated with enhanced lipogenesis, fatty acid uptake, and lipid metabolic …

Cholesterol homeostasis and cancer: a new perspective on the low-density lipoprotein receptor

J Gu, N Zhu, HF Li, TJ Zhao, CJ Zhang, DF Liao, L Qin - Cellular Oncology, 2022 - Springer
Background Disturbance of cholesterol homeostasis is considered as one of the
manifestations of cancer. Cholesterol plays an essential role in the pleiotropic functions of …

Bergapten ameliorates vincristine-induced peripheral neuropathy by inhibition of inflammatory cytokines and NFκB signaling

G Singh, A Singh, P Singh, R Bhatti - ACS Chemical Neuroscience, 2019 - ACS Publications
Bergapten, a furanocoumarin derivative found in a variety of medicinal plants, is
documented to possess anti-inflammatory activity. However, whether bergapten is useful in …

Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis …

X Zhang, Z Dong, Y Yang, C Liu, J Li… - Journal of Agricultural …, 2023 - ACS Publications
The incidence rate of colorectal cancer (CRC) has been increasing significantly in recent
years, and it is urgent to develop novel drugs that have more effects for its treatment. It has …

Ficus hirta Vahl. Ameliorates Nonalcoholic Fatty Liver Disease through Regulating Lipid Metabolism and Gut Microbiota

T Quan, F Zhou, H Chen, L Jian, Y Yang… - Oxidative Medicine …, 2022 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) has gradually become one of the most serious liver
diseases threatening human health in the world. Currently, Chinese herbal medicine is a …