Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities
G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
[HTML][HTML] The oralome and its dysbiosis: New insights into oral microbiome-host interactions
The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …
ecological community of oral microorganisms (comprised of up to approximately 1000 …
Oral polymicrobial communities: Assembly, function, and impact on diseases
G Hajishengallis, RJ Lamont, H Koo - Cell host & microbe, 2023 - cell.com
Oral microbial communities assemble into complex spatial structures. The sophisticated
physical and chemical signaling systems underlying the community enable their collective …
physical and chemical signaling systems underlying the community enable their collective …
Microbial transitions from health to disease
Recent advances in our understanding of the microbial populations that colonize the human
mouth, their acquisition, interdependency, and coevolution with the host, bring a different …
mouth, their acquisition, interdependency, and coevolution with the host, bring a different …
The “Gum–Gut” axis in inflammatory bowel diseases: a hypothesis-driven review of associations and advances
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper
airways and gastrointestinal tract; however, its connection to the rest of the body has been …
airways and gastrointestinal tract; however, its connection to the rest of the body has been …
Osteoimmunology in periodontitis and orthodontic tooth movement
B Alghamdi, HH Jeon, J Ni, D Qiu, A Liu… - Current osteoporosis …, 2023 - Springer
Abstract Purpose of Review To review the role of the immune cells and their interaction with
cells found in gingiva, periodontal ligament, and bone that leads to net bone loss in …
cells found in gingiva, periodontal ligament, and bone that leads to net bone loss in …
Illuminating the oral microbiome and its host interactions: animal models of disease
G Hajishengallis - FEMS Microbiology Reviews, 2023 - academic.oup.com
Periodontitis and caries are driven by complex interactions between the oral microbiome
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …
Social networking at the microbiome-host interface
RJ Lamont, G Hajishengallis, H Koo - Infection and Immunity, 2023 - Am Soc Microbiol
Microbial species colonizing host ecosystems in health or disease rarely do so alone.
Organisms conglomerate into dynamic heterotypic communities or biofilms in which …
Organisms conglomerate into dynamic heterotypic communities or biofilms in which …
Development and characterization of an oral microbiome transplant among Australians for the treatment of dental caries and periodontal disease: A study protocol
Background Oral microbiome transplantation (OMT) is a novel concept of introducing health-
associated oral microbiota into the oral cavity of a diseased patient. The premise is to …
associated oral microbiota into the oral cavity of a diseased patient. The premise is to …
[HTML][HTML] The prevalence of novel periodontal pathogens and bacterial complexes in Stage II generalized periodontitis based on 16S rRNA next generation sequencing
Objective: To define the subgingival microbial profile associated with Stage II generalized
periodontitis using next-generation sequencing and to determine the relative abundance of …
periodontitis using next-generation sequencing and to determine the relative abundance of …