Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

The canonical Wnt pathway is one of the key cellular signaling cascades that regulates, via
the transcriptional co-activator β-catenin, numerous embryogenic developmental processes …

This study aimed to develop microspheres using water-soluble carriers and surfactants to
improve the solubility, dissolution, and oral bioavailability of rivaroxaban (RXB). RXB-loaded …

Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …

The purpose of this study was to use hydroxypropyl-β-cyclodextrin (HP-β-CD) as a novel
carrier in solid SNEDDS and solid dispersions to enhance the solubility and oral …

Lipid based drug delivery systems (LBDDS) are valuable and biocompatible nano-carriers
for the vehiculation and potential delivery of various hydrophilic, hydrophobic, or amphiphilic …

Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical
Classification System (BCS) because of its poor aqueous solubility. In this study, we …

Background The purpose of this study was to screen various drug delivery systems for
improving the aqueous solubility and oral bioavailability of sildenafil. Three representative …

Oral delivery has become the route of choice among all other types of drug administrations.
However, typical chronic disease drugs are often poorly water-soluble, have low dissolution …

The second most significant cause of cancer-related mortality and morbidity in the United
States is colorectal cancer (CRC), the third most diagnosed malignancy. People over 50 …