Current approaches to monitor macromolecules directly from the cerebral interstitial fluid
ML Custers, L Nestor, D De Bundel, A Van Eeckhaut… - Pharmaceutics, 2022 - mdpi.com
Gaining insights into the pharmacokinetic and pharmacodynamic properties of lead
compounds is crucial during drug development processes. When it comes to the treatment of …
compounds is crucial during drug development processes. When it comes to the treatment of …
A novel microdialysis-dissolution/permeation system for testing oral dosage forms: a proof-of-concept study
A novel microdialysis-dissolution/permeation (MD/P) system was developed for the
biopharmaceutical assessment of oral drug formulations. This system consists of a side-by …
biopharmaceutical assessment of oral drug formulations. This system consists of a side-by …
[PDF][PDF] Current approaches to monitor macromolecules directly from the cerebral interstitial fluid. Pharmaceutics. 2022; 14: 1051
ML Custers, L Nestor, D De Bundel… - Brain-Targeted Drug …, 2022 - mdpi.com
Gaining insights into the pharmacokinetic and pharmacodynamic properties of lead
compounds is crucial during drug development processes. When it comes to the treatment of …
compounds is crucial during drug development processes. When it comes to the treatment of …
[HTML][HTML] Quantitative analysis of human brain microdialysate for target site pharmacokinetics of major anesthetics ketamine, midazolam and propofol
AS Guntner, W Buchberger, A Hosmann… - … of Pharmaceutical and …, 2021 - Elsevier
Brain microdialysis samples of intensive care patients treated with the essential anesthetics
ketamine, midazolam and propofol were investigated. Importantly, despite decades of …
ketamine, midazolam and propofol were investigated. Importantly, despite decades of …
Development and validation of an LC–MS/MS method for quantitative determination of GS87, a novel antineoplastic agent, in mouse plasma
SR Kunati, S Yang, D Wald, Y Xu - Journal of Pharmaceutical and …, 2018 - Elsevier
GS87 is a novel, highly specific GSK3 inhibitor, which has shown to induce extensive
differentiation of acute myeloid leukemia (AML) cells in early mouse studies and has great …
differentiation of acute myeloid leukemia (AML) cells in early mouse studies and has great …